From the Guidelines
The correct answer is D. Respect for persons, beneficence, and justice. The Belmont Report, published in 1979 by the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research, established these three fundamental ethical principles for human research protections, as outlined in a study published in the American Journal of Respiratory and Critical Care Medicine 1. Key aspects of these principles include:
- Respect for persons, which acknowledges individual autonomy and requires informed consent from research participants
- Beneficence, which obligates researchers to maximize benefits while minimizing harm to participants
- Justice, which ensures fair distribution of research benefits and burdens across populations These principles form the ethical foundation for modern clinical research regulations and are essential knowledge for anyone seeking GCP (Good Clinical Practice) certification, as they help researchers design and conduct studies that protect participants' rights and welfare while advancing scientific knowledge 1.
From the Research
Key Principles of Human Research Protections
The Belmont Report of 1979 established the key principles of human research protections as:
- Respect for persons
- Beneficence
- Justice
Correct Option
The correct option is: D. Respect for persons, beneficence, and justice.
Relevance of Provided Studies
None of the provided studies 2, 3, 4, 5, 6 directly address the key principles of human research protections established by the Belmont Report. Therefore, the answer is based on general knowledge of the topic.