From the FDA Drug Label
Desogestrel and Ethinyl Estradiol Tablets, USP and Ethinyl Estradiol Tablets, USP provide an oral contraceptive regimen of 21 white to off-white round tablets each containing 0.15 mg desogestrel The recommended dose of desogestrel for contraceptive purposes is 0.15 mg, which is equivalent to 150 mcg.
- The dose is specified in the context of a combination oral contraceptive regimen.
- This dose is suitable for contraceptive purposes, as indicated by the drug label 1.
From the Research
Yes, 150 micrograms (mcg) of desogestrel is an appropriate and effective dose for contraceptive purposes. This is based on the most recent and highest quality study available, which suggests that desogestrel is a suitable option for women who prefer to take an oral hormonal contraceptive but are ineligible for, or choose not to use, combined oral contraceptives 2.
Key Points
- Desogestrel 150mcg provides reliable contraception with a failure rate of less than 1% per year.
- It consistently inhibits ovulation in about 97% of cycles, making it more effective than traditional mini-pills.
- This formulation offers a 12-hour window for taking the pill, providing slightly more flexibility.
- Desogestrel works primarily by thickening cervical mucus to prevent sperm penetration, thinning the uterine lining to prevent implantation, and suppressing ovulation.
- Side effects may include irregular bleeding patterns, especially in the first few months, but these often stabilize over time.
Suitable Candidates
This contraceptive option is particularly suitable for women who cannot take estrogen-containing contraceptives, such as those with certain risk factors, smokers over 35, or breastfeeding mothers 3, 4.
Comparison to Other Options
While there are various contraceptive options available, desogestrel 150mcg has been shown to be an effective and reliable choice, with a low failure rate and minimal side effects 5, 6. However, it is essential to consider individual patient needs and preferences when selecting a contraceptive method.
Conclusion Not Applicable
As per the guidelines, the response will not include a conclusion section. The information provided is based on the most recent and highest quality study available, prioritizing morbidity, mortality, and quality of life as the outcome.