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Last updated: May 31, 2025View editorial policy

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Differential Diagnosis

  • Single most likely diagnosis
    • Acute Sinusitis: The patient's symptoms of sinus pressure, headache, and fullness in the ears, combined with a cough due to postnasal drip, are classic for acute sinusitis. The fact that seasonal allergy medications do not alleviate symptoms suggests that the cause may be infectious rather than allergic.
  • Other Likely diagnoses
    • Viral Upper Respiratory Infection (URI): The symptoms could also be consistent with a viral URI, which often presents with similar symptoms including cough, headache, and nasal congestion.
    • Allergic Rhinitis: Although the patient's seasonal allergy medications do not change symptoms, it's possible that the medications are not effective or that the patient has developed new allergies.
    • Eustachian Tube Dysfunction: This condition can cause fullness in the ears and is often associated with nasal congestion and sinus pressure.
  • Do Not Miss diagnoses
    • Bacterial Sinusitis with Complications (e.g., orbital cellulitis, cavernous sinus thrombosis): Although less likely, it's crucial to consider the possibility of bacterial sinusitis, especially if symptoms worsen or do not improve with treatment, as complications can be severe and life-threatening.
    • Mastoiditis: This is an infection of the mastoid bone in the skull, which can cause symptoms similar to those described, including ear fullness and headache.
  • Rare diagnoses
    • Sarcoidosis: A systemic disease that can cause sinusitis and other respiratory symptoms, although it would be an unusual presentation.
    • Wegener's Granulomatosis (Granulomatosis with Polyangiitis): A rare autoimmune disorder that can cause sinusitis, although other systemic symptoms would typically be present.
    • Tumors (e.g., nasopharyngeal carcinoma): Although extremely rare, tumors in the nasal cavity or sinuses can cause similar symptoms and should be considered if symptoms persist or worsen despite treatment.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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