What is the recommended treatment for a urinary tract infection caused by Staphylococcus haemolyticus?

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Last updated: June 1, 2025View editorial policy

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From the Research

The recommended treatment for a urinary tract infection (UTI) caused by Staphylococcus haemolyticus typically involves antibiotics such as nitrofurantoin (100mg orally every 12 hours for 5-7 days) or vancomycin (15-20mg/kg IV every 8-12 hours), as S. haemolyticus often shows resistance to multiple antibiotics, including methicillin. According to the most recent study 1, nitrofurantoin had a high susceptibility rate against Gram-positive isolates, including Staphylococcus haemolyticus. Key considerations for treatment include:

  • Antimicrobial susceptibility testing to guide treatment
  • Increased fluid intake to help flush bacteria from the urinary tract
  • Potential use of phenazopyridine (200mg orally three times daily for 2 days) for pain relief
  • Awareness of the risk of biofilm formation on urinary catheters and medical devices, which can make infections more difficult to treat. It is also important to note that the use of fluoroquinolones like ciprofloxacin may be limited due to high resistance rates, as reported in a recent study 2. Overall, treatment should be tailored to the individual patient and guided by the results of antimicrobial susceptibility testing, with a focus on minimizing the risk of complications and promoting optimal outcomes.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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