What is the treatment for axillary (armpit) fungal infections?

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From the Guidelines

Treatment for axillary fungal infections typically involves antifungal medications applied directly to the affected area, starting with over-the-counter topical antifungals like clotrimazole 1% (Lotrimin), miconazole 2% (Monistat), or terbinafine 1% (Lamisil) cream. Applying a thin layer to clean, dry skin twice daily for 2-4 weeks, even if symptoms improve sooner, is usually recommended. For more severe infections, prescription-strength options include econazole nitrate 1% cream, ketoconazole 2% cream, or ciclopirox 0.77% cream.

Some key points to consider:

  • Keep the armpit area clean and dry, as fungi thrive in warm, moist environments.
  • Wear loose-fitting, breathable clothing and change clothes after sweating.
  • Use separate towels for the infected area to prevent spread.
  • Consider using antifungal powders like miconazole or clotrimazole powder to help keep the area dry.
  • If the infection doesn't improve after two weeks of treatment, shows signs of bacterial infection (increased redness, warmth, pain), or if you have diabetes or a weakened immune system, consult a healthcare provider as oral antifungal medications may be necessary 1.

It's also important to note that while there are various treatment options available, the most effective approach may vary depending on the severity of the infection and the individual's overall health. Therefore, it's essential to consult a healthcare provider for personalized advice and guidance.

In terms of specific treatment regimens, some studies suggest that fluconazole may be an effective option for certain types of fungal infections 1. However, it's crucial to follow the recommended dosage and treatment duration to ensure optimal outcomes.

Overall, a comprehensive approach to treating axillary fungal infections involves a combination of topical antifungal medications, good hygiene practices, and potentially oral antifungal medications in severe cases. By following these guidelines and consulting a healthcare provider as needed, individuals can effectively manage their symptoms and prevent future infections.

From the FDA Drug Label

INDICATIONS AND USAGE Griseofulvin oral suspension, USP is indicated for the treatment of dermatophyte infections of the skin not adequately treated by topical therapy, hair and nails, namely: Tinea corporis Tinea pedis Tinea cruris The first line therapy for axillary (armpit) fungal infections, also known as Tinea cruris or jock itch, is typically topical therapy.

  • The drug label for griseofulvin 2 does not specify it as a first line treatment for Tinea cruris, but rather as an option when the infection is not adequately treated by topical therapy.
  • Griseofulvin is an oral antifungal medication that may be used for more severe cases of dermatophyte infections, including Tinea cruris.

From the Research

First Line Therapy for Armpit Fungal Infections

The treatment for axillary (armpit) fungal infections typically involves topical antifungal agents.

  • Topical therapies are effective in treating fungal infections of the skin surface, including those in the armpit area 3.
  • Azole drugs such as miconazole, clotrimazole, and ketoconazole are commonly used to treat fungal infections, including those caused by yeast 3, 4.
  • Allylamines and benzylamines such as terbinafine are also effective in treating dermatophytic fungal infections, but may not be as effective against yeast infections 3.

Topical Antifungal Agents

Some key points to consider when selecting a topical antifungal agent include:

  • The type of fungal infection (e.g. dermatophyte, yeast)
  • The severity of the infection
  • The patient's preference for formulation (e.g. cream, lotion, spray)
  • Cost and availability of the medication 3, 4
  • Fungicidal drugs, such as allylamines and benzylamines, are often preferred over fungistatic drugs for treatment of dermatophytic fungal infections, as they can provide shorter treatment times and higher cure rates 3.

Systemic Antifungal Agents

In some cases, systemic antifungal agents may be necessary to treat more severe or widespread fungal infections.

  • Systemic antifungal agents, such as itraconazole and terbinafine, may be used to treat chronic or relapsing dermatophytic infections 5, 6.
  • However, the effectiveness of these agents can vary depending on the specific infection and patient population 5, 7.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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