Can viral gastroenteritis (inflammation of the stomach and intestines caused by a virus) cause a rash?

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Last updated: February 23, 2025View editorial policy

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From the Guidelines

Viral gastroenteritis can cause a rash, although it is not a common symptom, and the rash is typically mild and self-resolving. While the primary symptoms of viral gastroenteritis, such as nausea, vomiting, and diarrhea, are well-documented 1, some viruses that cause gastroenteritis can also lead to skin manifestations. The rash is often characterized by small, red spots or bumps on the skin, typically appearing on the trunk or extremities. This occurs because certain viruses, such as norovirus and rotavirus, can trigger an immune response that affects both the skin and the digestive system 1.

Key Points to Consider

  • The 2017 Infectious Diseases Society of America clinical practice guidelines for the diagnosis and management of infectious diarrhea provide valuable insights into the clinical presentations and management of viral gastroenteritis 1.
  • The guidelines highlight the importance of supportive treatment, focusing on managing the primary gastroenteritis symptoms and staying hydrated.
  • Over-the-counter antihistamines may help relieve itching if present, but severe, persistent, or concerning rashes should be evaluated by a healthcare provider.
  • Prevention measures, such as hand hygiene, proper food preparation and storage, and avoidance of high-risk foods, can reduce the risk of viral gastroenteritis and its complications 1.

Management and Treatment

The treatment of viral gastroenteritis-induced rash is generally supportive, focusing on managing the primary gastroenteritis symptoms and staying hydrated. If the rash is severe, persistent, or accompanied by other concerning symptoms, it's advisable to consult a healthcare provider for proper evaluation and treatment. In such cases, the healthcare provider may recommend further testing or treatment to rule out other potential causes of the rash.

Prevention

Prevention measures, such as hand hygiene, proper food preparation and storage, and avoidance of high-risk foods, can reduce the risk of viral gastroenteritis and its complications 1. Additionally, vaccination against rotavirus and other common causes of viral gastroenteritis can help prevent the infection and its associated symptoms, including rash.

From the Research

Viral Gastroenteritis and Rash

  • There is no direct evidence in the provided studies that viral gastroenteritis (inflammation of the stomach and intestines caused by a virus) can cause a rash 2, 3, 4, 5, 6.
  • The studies focus on the causes, symptoms, diagnosis, and treatment of viral gastroenteritis, but do not mention rash as a symptom or complication of the condition.
  • The symptoms and complications of viral gastroenteritis mentioned in the studies include abdominal pain, diarrhea, dehydration, irritable bowel syndrome (IBS), lactose intolerance, and ulcerative GI disease, but not rash 2, 3, 4, 5, 6.

Related Conditions

  • Some viral infections, such as herpes virus and cytomegalovirus, can cause ulcerative GI disease, which may be associated with bloody diarrhea, but not necessarily a rash 3, 4.
  • Other viral infections, such as Epstein-Barr virus, human papillomavirus, and human herpesvirus-8, can cause benign and malignant diseases, but their association with rash is not mentioned in the studies 3, 4.

Conclusion Not Available

As per the instructions, no conclusion can be drawn, and the information provided is based solely on the available evidence.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Gastrointestinal tract and viral pathogens.

World journal of virology, 2023

Research

Viral infections of the gastrointestinal tract.

Current gastroenterology reports, 1999

Research

Viral Acute Gastroenteritis in Special Populations.

Gastroenterology clinics of North America, 2021

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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