From the Guidelines
The treatment for intertrigo involves keeping the affected skin folds clean, dry, and separated, and using topical azoles and polyenes, including clotrimazole, miconazole, and nystatin, as they are effective in treating candidal skin infections and intertrigo. When managing intertrigo, it is essential to consider the following key points:
- Keeping the infected area dry is crucial, as fungi and bacteria thrive in warm, moist environments 1.
- Topical antifungals, such as clotrimazole, miconazole, and nystatin, are effective in treating intertrigo, especially in obese and diabetic patients who are prone to candidal skin infections 1.
- In addition to antifungal treatment, gentle washing with mild soap and water, followed by thorough drying, can help prevent the growth of microorganisms.
- Applying zinc oxide, petroleum jelly, or antifungal powders to the area 2-3 times daily for 1-2 weeks can also be beneficial.
- For more severe cases, low-potency topical steroids like hydrocortisone 1% can reduce inflammation for 3-7 days.
- Wearing loose-fitting, breathable clothing and using cotton fabric to absorb moisture between skin folds can help prevent moisture buildup and reduce the risk of intertrigo. It is essential to note that if symptoms worsen or do not improve within two weeks, medical evaluation is necessary, as stronger prescription medications may be needed.
From the Research
Treatment for Intertrigo
The treatment for intertrigo typically involves a combination of measures to reduce moisture, friction, and bacterial or fungal infections. Some of the key treatment options include:
- Topical antifungal agents such as nystatin, clotrimazole, ketoconazole, oxiconazole, or econazole to treat fungal lesions 2, 3
- Topical mupirocin or oral penicillin to treat secondary streptococcal infections 2
- Oral erythromycin to treat Corynebacterium infections 2
- Oral fluconazole therapy for resistant cases of candidal intertrigo 2
- Moisture-wicking textiles to reduce skin-on-skin friction and wick away moisture 4
- Structured skin care routine and education on skin fold management to prevent and manage intertrigo 4, 5
Management and Prevention
In addition to treatment, management and prevention of intertrigo are crucial. This can be achieved by:
- Identifying and addressing predisposing factors such as obesity and poor air circulation 4, 5
- Educating patients on skin fold management and adopting a structured skin care routine 4, 5
- Using topical agents to treat secondary infections 2, 3
- Considering the use of moisture-wicking textiles to reduce skin-on-skin friction and prevent secondary infection 4
Evidence Base
The evidence base for the treatment and management of intertrigo is limited, with a need for well-designed studies to test proposed interventions and build a robust evidence base 4, 6. However, consensus among health professionals suggests that a combination of measures to reduce moisture, friction, and bacterial or fungal infections, along with education and structured skin care, can improve patient outcomes 4, 5.