What are the treatment options for Seborrheic (seborrheic) dermatitis?

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Last updated: February 23, 2025View editorial policy

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From the Guidelines

Seborrheic dermatitis can be effectively managed with topical antifungal medications and anti-inflammatory agents, prioritizing treatments that reduce Malassezia yeast and inflammation. When considering treatment options for seborrheic dermatitis, it's essential to focus on managing the underlying causes, including the overgrowth of Malassezia yeast and the resulting inflammation 1. Key treatment strategies include:

  • Using topical antifungal medications to reduce the amount of yeast present
  • Applying topical anti-inflammatory medications to reduce inflammation and itch
  • Maintaining good skin care practices, such as gentle cleansing and moisturizing, to prevent dryness and flaking While the provided evidence does not specify particular antifungal or anti-inflammatory agents, a common approach includes using antifungal shampoos containing ketoconazole or selenium sulfide, and topical corticosteroids like hydrocortisone to reduce inflammation 1. It's crucial to note that seborrheic dermatitis is a chronic condition, and consistent treatment is necessary to manage symptoms and prevent flare-ups. In cases where symptoms persist or worsen, consulting a dermatologist for further evaluation and potential adjustments to the treatment plan is recommended. Regular follow-up and adherence to the treatment regimen can significantly improve the quality of life for individuals with seborrheic dermatitis, reducing morbidity and mortality associated with complications or comorbidities.

From the FDA Drug Label

DOSAGE & ADMINISTRATION SECTION ... Seborrheic dermatitis: Ketoconazole Cream 2% should be applied to the affected area twice daily for four weeks or until clinical clearing. Purpose Anti-dandruff, anti-seborrheic dematitis, anti-psoriasis

The treatment options for Seborrheic dermatitis include:

  • Ketoconazole Cream 2% applied twice daily for four weeks or until clinical clearing 2
  • Coal tar for anti-seborrheic dermatitis treatment 3

From the Research

Treatment Options for Seborrheic Dermatitis

The treatment options for seborrheic dermatitis include:

  • Topical corticosteroids 4, 5, 6, 7
  • Antifungal agents such as topical ketoconazole 6, 7
  • Calcineurin inhibitors such as pimecrolimus 1% cream 5 and topical tacrolimus 8
  • Shampoos containing zinc pyrithione 8, 7 or selenium sulfide 7
  • Topical sodium sulfacetamide 7
  • Terbinafine solution 7
  • Psoralen plus UVA 5
  • Oral antifungals 5

Treatment for Specific Areas

For the scalp, treatment options include:

  • Antifungal shampoos (long-term) 6
  • Topical corticosteroids (short-term) 6
  • Shampoos containing zinc pyrithione 8, 7 or selenium sulfide 7 For the face and body, treatment options include:
  • Antifungal agents such as topical ketoconazole 6
  • Topical corticosteroids (short-term) 6
  • Calcineurin inhibitors such as pimecrolimus 1% cream 5

Combination Therapy

Combination therapy of topical steroid or topical tacrolimus, and zinc pyrithione is recommended for treating seborrheic dermatitis of the scalp 8

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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