From the Research
Borate bioactive glass products facilitate wound healing through multiple mechanisms that promote tissue regeneration, including the release of ions such as calcium, sodium, and boron that stimulate cellular responses critical for healing, as demonstrated in a study published in 2022 1. These specialized glass materials dissolve at a controlled rate when in contact with wound fluids, creating an antibacterial environment that helps prevent infection while also promoting angiogenesis (formation of new blood vessels), which is essential for delivering oxygen and nutrients to healing tissues. Some key benefits of borate bioactive glass products in wound healing include:
- Promotion of angiogenesis, as shown in a study published in 2018 2
- Stimulation of fibroblast proliferation and collagen deposition, which are necessary for rebuilding the extracellular matrix in damaged tissue
- Creation of a gel-like layer that provides a scaffold for cell migration and tissue growth
- Controlled ion release that creates an optimal biochemical environment, accelerating the natural healing process while reducing inflammation and scarring, as discussed in a review published in 2020 3 Products like borate-based wound dressings can be applied directly to wounds and left in place, as they gradually dissolve and become incorporated into the healing tissue, making them particularly effective for chronic wounds, diabetic ulcers, and burns where conventional treatments may be less successful. The use of borate bioactive glass products in wound healing is supported by various studies, including one published in 2017 4 that highlighted the potential of bioactive glasses in wound healing, and another published in 2015 5 that demonstrated the ability of copper-doped borate bioactive glass microfibers to stimulate angiogenesis and heal full-thickness skin defects in a rodent model.