What are the signs and symptoms of radial artery aneurysm after cardiac catheterization?

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Last updated: June 4, 2025View editorial policy

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From the Guidelines

Radial artery aneurysm after cardiac catheterization is a rare but potentially serious complication that typically presents with a pulsatile mass or swelling at the catheterization site, accompanied by pain, tenderness, or discomfort in the wrist area, as reported in the 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention 1. The signs and symptoms of radial artery aneurysm after cardiac catheterization may include:

  • A visible bulge that expands with each heartbeat
  • Redness, warmth, or bruising around the site
  • Paresthesia (numbness or tingling) in the hand or fingers due to compression of nearby nerves
  • Diminished pulse distal to the aneurysm
  • Compromised circulation to the hand
  • Skin ulceration over the aneurysm These symptoms usually develop within days to weeks after the procedure, though some may appear months later. The aneurysm forms due to incomplete sealing of the arterial puncture site, allowing blood to leak into surrounding tissues and form a contained hematoma that communicates with the arterial lumen. Risk factors for radial artery aneurysm include inadequate compression after catheter removal, anticoagulation therapy, multiple puncture attempts, and large catheter size, as discussed in the context of vascular complications from PCI in the 2011 guideline 1. Any persistent or growing mass at a catheterization site should be promptly evaluated with ultrasound to confirm the diagnosis and determine appropriate management. It is worth noting that the incidence of vascular complications, including radial artery aneurysm, has decreased with time and the use of radial site access, which decreases the rate of access-related bleeding and complications compared with femoral access, as reported in the 2011 ACCF/AHA/SCAI guideline 1.

From the Research

Signs and Symptoms of Radial Artery Aneurysm

  • Pain
  • Swelling
  • Haematoma of the arm 2

Diagnosis

  • Doppler ultrasonography is used to diagnose radial artery pseudoaneurysm 2, 3

Treatment Options

  • Surgical treatment has been considered the gold standard, but new and less invasive strategies have been proposed, including:
    • Ultrasound-guided compression 4, 3
    • Local injection of thrombin 2, 5, 6
    • Manual compression protocols using the TR Band 4
    • Ultrasound-guided differential compression 3

Predictors of Treatment Failure

  • Age: younger age is a predictor of primary failure 6
  • Anteroposterior diameter: larger diameter is a predictor of primary failure 6
  • Neck diameter: larger diameter is a predictor of primary failure 6

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Radial pseudoaneurysm in elderly: a rare event with undefinied therapeutical approach. A case report and literature review.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2019

Research

Radial Artery Pseudoaneurysms Treated by Ultrasound-Guided Differential Compression: An Effective and Simple Method.

Heart views : the official journal of the Gulf Heart Association, 2019

Research

Radial artery pseudoaneurysm: a simplified treatment method.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2014

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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