Ventilator Settings for a 20 kg Child
For a 20 kg child requiring mechanical ventilation, use a tidal volume of ≤10 mL/kg ideal body weight (approximately 140-200 mL), PEEP of 5-8 cmH₂O, peak inspiratory pressure ≤28-30 cmH₂O, and target SpO₂ of 92-97% based on disease severity. 1
Core Ventilator Parameters
Tidal Volume
- Set at ≤10 mL/kg ideal body weight (for a 20 kg child: approximately 140-200 mL maximum)
- Consider lower volumes (maybe <10 mL/kg) in lung hypoplasia syndromes
- Use predicted body weight, not actual body weight, for calculations 1
Pressure Limits
- Plateau pressure: Keep ≤28-30 cmH₂O in most conditions
- With increased chest wall elastance: ≤29-32 cmH₂O acceptable
- In obstructive airway disease: ≤30 cmH₂O
- Driving pressure: Keep ≤10 cmH₂O for healthy lungs 1
PEEP Settings
- Start with 5-8 cmH₂O as baseline
- Higher PEEP necessary when dictated by underlying disease severity
- Use PEEP titration and consider lung recruitment maneuvers
- In obstructive airway disease with air-trapping: add PEEP to facilitate triggering
- Use PEEP to stent upper airways if malacia present 1
Respiratory Rate
- Set inspiratory time based on respiratory system mechanics and underlying disease
- Use time constant and observe flow-time scalar
- Use higher rates in restrictive disease 1
Oxygenation Targets (Disease-Specific)
For Healthy Lungs
- SpO₂ ≥95% when breathing room air
- PCO₂ 35-45 mmHg 1
For PARDS (Pediatric ARDS)
- SpO₂ 92-97% when PEEP <10 cmH₂O
- SpO₂ 88-92% when PEEP ≥10 cmH₂O
- Keep SpO₂ ≤97% in all disease conditions to avoid hyperoxia 1
For Other Acute Conditions
- Higher PCO₂ accepted unless specific diseases dictate otherwise
- Target pH >7.20 (except pulmonary hypertension—target normal pH) 1
Critical Monitoring Requirements
For children <10 kg: Measure pressures near Y-piece of patient circuit 1
Essential Monitoring
- End-tidal CO₂ in all ventilated children
- SpO₂ in all ventilated children
- Peak inspiratory pressure and/or plateau pressure
- Mean airway pressure
- Positive end-expiratory pressure 1
In Moderate-to-Severe Disease
- Arterial PO₂
- pH, lactate, and central venous saturation
- Consider transpulmonary pressure and dynamic compliance
- Monitor pressure-time and flow-time scalars 1
Equipment Specifications
Airway Management
- Use cuffed endotracheal tube
- Keep cuff pressure ≤20 cmH₂O
- Minimize dead space by added components
- Use double-limb circuits for invasive ventilation 1
Supportive Measures
- Use humidification (mandatory)
- Maintain head of bed elevated 30-45°
- Do not perform endotracheal suctioning routinely—only on indication
- No routine instillation of isotonic saline prior to suctioning 1
Mode Selection Strategy
Target patient-ventilator synchrony as primary goal 1
The 2017 PEMVECC guidelines 1 provide the most comprehensive pediatric-specific recommendations and emphasize that these principles apply across cardiac and non-cardiac patients alike. The key distinction from adult ventilation is the weight-based calculations and the specific pressure limits that account for pediatric chest wall compliance.
Common Pitfalls to Avoid
- Using actual body weight instead of ideal/predicted body weight for tidal volume calculations—this leads to excessive volumes
- Limiting PEEP to <5 cmH₂O—insufficient to prevent atelectasis in most disease states
- Allowing plateau pressures >30 cmH₂O without increased chest wall elastance
- Targeting SpO₂ >97%—risks hyperoxia-related injury
- Routine suctioning—increases risk of ventilator-associated complications 1