Cardiovascular OSCE History of Present Illness Questionnaire
A comprehensive cardiovascular HPI questionnaire should systematically capture chest pain characteristics using the OPQRST framework (Onset, Provocation/Palliation, Quality, Radiation, Severity, Timing), followed by structured assessment of cardiac risk factors, past cardiac history, medications, and social determinants. 1, 2
Patient Demographics
- Age: _____
- Sex: _____
- Date/Time of presentation: _____
Chief Complaint
Presenting symptom: (e.g., chest pain, dyspnea, palpitations, syncope)
History of Present Illness - Pain Characteristics
Onset & Duration
- When did symptoms begin? (exact time/date)
- Mode of onset: Gradual (builds over minutes) vs. Sudden/hyperacute
- Duration of current episode: Seconds / Minutes / Hours / Days
- Pattern: First episode / Recurrent / Worsening over time
Location
- Primary site: Retrosternal / Left chest / Right chest / Epigastric / Other
- Can you point to it with one finger? (If yes, less likely cardiac) 2
Radiation
- Does pain spread elsewhere?
Quality/Character
- Describe the sensation:
Severity
- Rate pain 0-10: _____
- Intensity at onset: Maximal immediately vs. gradual buildup
Timing/Temporal Pattern
- Frequency: Constant / Intermittent / Episodic
- Duration of episodes: <5 minutes (typical angina) / >20 minutes (ACS concern) / Fleeting seconds (unlikely cardiac) 2
- Time of day pattern: At rest / During sleep / Morning predominance
Provocative & Palliative Factors
Aggravating Factors
- Physical exertion (walking, stairs, specific activity level in METs) 6
- Emotional stress
- Cold exposure
- Large meals
- Lying supine (consider pericarditis if worsens)
- Inspiration/coughing (pleuritic - LR 0.2 against ACS) 3
- Position changes (musculoskeletal if reproducible)
- Palpation of chest wall (LR 0.2-0.3 against ACS) 3
Relieving Factors
- Rest (typical angina relieves in <5 minutes) 4
- Nitroglycerin (note: not diagnostic - can relieve esophageal spasm) 2
- Position changes
- Antacids
- Nothing relieves it
Associated Symptoms
Cardiac-Related
- Dyspnea (at rest / on exertion)
- Palpitations (regular / irregular / rate)
- Diaphoresis (profuse sweating)
- Nausea/vomiting
- Lightheadedness/presyncope
- Syncope (timing, duration, prodrome)
- Fatigue/weakness
- Polyuria (atrial natriuretic peptide release with AF) 7
Red Flag Symptoms
- Altered mental status (cardiogenic shock concern) 1
- Cold extremities (reduced cardiac output) 1
- Orthopnea/PND (heart failure)
- Peripheral edema
Atypical Presentations (Women, Elderly, Diabetics)
- Isolated epigastric discomfort/indigestion 1, 8
- Isolated jaw/neck pain
- Isolated arm pain
- Generalized weakness
- Confusion 8
Past Cardiac History
Prior Diagnoses
- Coronary artery disease: Yes / No / Unknown
- Prior myocardial infarction: (date, location, treatment)
- Prior PCI/stenting: (date, vessels)
- Prior CABG: (date, number of grafts)
- Angina: Stable / Unstable / Variant
- Heart failure: (NYHA class, EF if known)
- Valvular disease: (specify valve, severity)
- Arrhythmias: AF / VT / Other (specify)
- Cardiomyopathy: Dilated / Hypertrophic / Other
- Congenital heart disease
- Pericarditis/myocarditis
Prior Cardiac Testing
- Stress test: (date, result)
- Echocardiogram: (date, key findings)
- Cardiac catheterization: (date, findings)
- CT coronary angiography
Cardiovascular Risk Factors 9
Hypertension
- Diagnosed hypertension: Yes / No / Unknown
- Current BP: / mmHg
- Treatment: Medication / Diet / Exercise / None
- Controlled: Yes / No
Dyslipidemia
- Diagnosed: Yes / No / Unknown
- Most recent lipids:
- Total cholesterol: _____ mg/dL (>200 abnormal)
- LDL: _____ mg/dL (≥130 abnormal)
- HDL: _____ mg/dL (<40 men, <50 women abnormal)
- On lipid-lowering therapy: Yes / No
Diabetes Mellitus
- Type: Type 1 / Type 2 / None / Unknown
- Duration: _____
- Treatment: Insulin / Oral agents / Diet / None
- Most recent HbA1c or fasting glucose: _____
Tobacco Use 9
- Current smoker: (within 1 month)
- Former smoker: (quit >3 months ago, pack-years: _____)
- Never smoker
- Other tobacco: Cigars / Chewing tobacco / Vaping
Family History
- First-degree relatives with premature CAD (<55 years men, <65 years women): 9
- MI / Angina / CABG / PCI / Sudden cardiac death
- Specify: Relationship _____ Age at event _____
Other Risk Factors
- Chronic kidney disease: Stage _____ (GFR: _____) 9
- Peripheral arterial disease
- Prior stroke/TIA
- Obesity: BMI _____ kg/m²
- Sedentary lifestyle (activity level in METs) 9
- Obstructive sleep apnea
- Chronic inflammatory conditions
Medications
Current Cardiac Medications
- Antiplatelet agents: Aspirin / Clopidogrel / Other
- Anticoagulants: Warfarin / DOAC (specify)
- Beta-blockers: (name, dose)
- ACE inhibitors/ARBs: (name, dose)
- Statins: (name, dose)
- Nitrates: (short-acting / long-acting)
- Calcium channel blockers
- Diuretics
- Antiarrhythmics
Other Medications
- Diabetes medications
- Antihypertensives
- Recent medication changes
Recent Medication Use
- Aspirin in past 7 days: Yes / No (TIMI risk factor) 6
- Nitroglycerin use for this episode: Response _____
Allergies
- Drug allergies: (specify reaction)
- Contrast allergy
Social History
Substance Use
- Alcohol: Drinks/week _____ Pattern _____
- Illicit drugs:
- Cocaine (sympathomimetic, increases O₂ demand) 4
- Methamphetamine
- Other stimulants
Functional Status
- Baseline activity level: Sedentary / Light / Moderate / Vigorous
- Recent change in exercise tolerance: Yes / No
- Able to climb stairs: Yes / No (how many flights)
- Can perform ADLs independently: Yes / No
Occupational/Environmental
- Occupation: (physical demands)
- Recent stressors
Review of Systems (Cardiac-Focused)
Signs of Heart Failure
- Orthopnea (number of pillows)
- Paroxysmal nocturnal dyspnea
- Peripheral edema (location, pitting)
- Weight gain (amount, timeframe)
- Decreased urine output
Signs of Reduced Cardiac Output 1
- Tachycardia
- Hypotension
- Cool extremities
- Altered mental status
Other Vascular Symptoms
- Claudication
- Abdominal pain (mesenteric ischemia)
- Neurologic symptoms (stroke/TIA)
Clinical Pitfalls to Avoid
Common diagnostic errors: 10, 5
- Missing aortic dissection by not asking all 5 pain characteristics (character, onset, duration, radiation, severity) - asking <2 questions increases missed diagnosis 4-fold 5
- Gender bias - female patients with cardiac symptoms are more likely to receive incorrect diagnoses even with identical presentations 10
- Relying on nitroglycerin response as diagnostic (non-specific) 2
- Dismissing sharp/stabbing pain entirely (atypical presentations occur, especially in women/elderly/diabetics) 1, 8
- Failing to document negative findings (pleuritic, positional, reproducible pain helps rule out ACS) 3
Risk Stratification Context
TIMI Risk Score elements to calculate: 6
- Age ≥65 years
- ≥3 CAD risk factors
- Known CAD (stenosis ≥50%)
- ST deviation on ECG
- ≥2 anginal events in prior 24 hours
- Aspirin use in prior 7 days
- Elevated cardiac biomarkers
High-risk features requiring immediate ED transfer: 4, 8
- Prolonged rest pain (>20 minutes)
- Hemodynamic instability
- New heart failure signs
- New murmur (VSD/MR)
- Sustained ventricular arrhythmias