Can a hypertrophic (keloid) scar resolve on its own?

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Last updated: February 24, 2025View editorial policy

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From the Research

Hypertrophic scars typically don't completely resolve on their own, but they can significantly improve over time with proper treatment. The most recent and highest quality study, published in 2023 1, suggests that intralesional injections, particularly the combination of 5-fluorouracil and triamcinolone, may be the most effective treatment option for keloids and hypertrophic scars.

Treatment Options

Some key treatment options for hypertrophic scars include:

  • Silicone-based products (gels or sheets) applied daily for several months
  • Corticosteroid injections administered by a dermatologist every 4-6 weeks for 3-6 months
  • Laser therapy sessions spaced 4-6 weeks apart for 3-6 treatments
  • Gentle massage of the scar for 5-10 minutes daily and keeping the area moisturized

Importance of Treatment

It's essential to note that while complete resolution is uncommon, many people achieve satisfactory improvement with consistent treatment and patience. The scar will likely flatten and become less noticeable as collagen remodels over time. Protecting the scar from sun exposure is also crucial to prevent further discoloration.

Recent Findings

A recent systematic review and meta-analysis published in 2022 2 found that silicone and laser modalities improved Vancouver Scar Scale (VSS) scores, and intralesional triamcinolone combined with silicone or 5-fluorouracil was superior to intralesional triamcinolone monotherapy. Another study published in 2016 3 also highlighted the effectiveness of silicone, pulsed-dye laser, CO2 laser, corticosteroids, 5-fluorouracil, bleomycin, and scar massage in treating hypertrophic scars.

Quality of Life

The treatment of hypertrophic scars and keloids can have a significant impact on quality of life, as these scars can cause functional and aesthetic impairment. Therefore, it's crucial to prioritize treatment options that can improve the appearance and symptoms of these scars, ultimately enhancing the patient's quality of life.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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