Which of the following statements about sexually transmitted diseases is true?

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Last updated: September 16, 2026 • View editorial policy

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The Correct Answer is C: The Patient's Sexual Partners Must Be Informed to Prevent Transmission

Partner notification is a fundamental principle of STD management and control, as breaking the chain of transmission is crucial to preventing further spread of infection. 1

Why Option C is Correct

The CDC STD Treatment Guidelines explicitly state that "patients with STDs should ensure that their sex partners, including those without symptoms, are referred for evaluation" and that "breaking the chain of transmission is crucial to STD control" 1. Two established strategies exist for partner notification:

  • Patient referral: Index patients notify their partners directly
  • Provider referral: Health department staff notify partners named by infected patients

For selected STDs—particularly HIV, syphilis, gonorrhea, and chlamydia—health departments can assist in notifying partners while protecting patient confidentiality 1. Partners should be examined and treated even without clinical signs of infection and before laboratory results are available 1.

For HIV specifically, if a patient refuses to notify partners while continuing to place them at risk, physicians have an ethical and legal responsibility to inform persons at risk—though this "duty-to-warn" should be a last resort 1.

Why the Other Options are Incorrect

Option A is FALSE: Screening for syphilis and HIV should be performed broadly, not only under specific conditions. All pregnant women should be screened for syphilis during early pregnancy, with repeat screening in the third trimester and at delivery for high-risk patients 1. Universal screening is recommended in many populations.

Option B is FALSE: STDs are frequently polymicrobial infections, not monomicrobial. Patients often have coinfections with multiple pathogens, which is why comprehensive testing is important.

Option D is FALSE: Most STD patients are asymptomatic or have mild symptoms. The guidelines emphasize that partners "including those without symptoms" need evaluation 1, and many infections go unrecognized because they lack acute severe presentations. This asymptomatic nature is precisely why partner notification and screening are so critical.

Key Clinical Pitfall

The most common error is failing to address partner notification systematically. Clinicians must actively facilitate partner notification rather than assuming patients will handle it independently, as this directly impacts disease control and prevents reinfection of the index patient.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.