Does unilateral nephrectomy (removal of one kidney) preclude pacemaker (permanent artificial cardiac pacemaker) extraction?

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Last updated: February 24, 2025View editorial policy

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From the Guidelines

Having only one kidney does not preclude pacemaker extraction, and the procedure can be performed safely with proper precautions. The decision to proceed with pacemaker extraction should be based on a comprehensive assessment of the patient's health, weighing the necessity of the procedure against any potential risks associated with having a single kidney. Prior to the extraction, a thorough evaluation of kidney function is essential, including tests like serum creatinine and estimated glomerular filtration rate (eGFR) 1. The surgical team should be aware of the patient's single-kidney status to adjust medication dosages, particularly for antibiotics and pain management drugs that are cleared by the kidneys.

During the procedure, careful monitoring of fluid balance and electrolytes is crucial. Post-operative care should include close observation of kidney function and urine output. While having one kidney doesn't directly affect the heart or the pacemaker system, it may influence overall health status and recovery. According to the 2014 AHA/ACC guideline for the management of patients with valvular heart disease, complete removal of pacemaker or defibrillator systems, including all leads and the generator, is reasonable in patients with valvular IE caused by S. aureus or fungi, even without evidence of device or lead infection 1.

Key considerations for pacemaker extraction in patients with a single kidney include:

  • Thorough evaluation of kidney function before the procedure
  • Adjustment of medication dosages based on kidney function
  • Careful monitoring of fluid balance and electrolytes during the procedure
  • Close observation of kidney function and urine output post-operatively
  • Comprehensive assessment of the patient's health to weigh the necessity of the procedure against potential risks.

From the Research

Unilateral Nephrectomy and Pacemaker Extraction

  • There is no direct evidence to suggest that unilateral nephrectomy (removal of one kidney) precludes pacemaker extraction 2, 3, 4, 5, 6.
  • The provided studies discuss various aspects of pacemaker implantation, lead extraction, and the management of patients with cardiac rhythm devices, but do not specifically address the relationship between unilateral nephrectomy and pacemaker extraction.
  • Studies have shown that leadless pacemakers may be a preferred option for patients with limited vascular access and high-infection risk, such as those on hemodialysis 5.
  • The extraction of cardiac rhythm devices is a complex procedure that requires careful consideration of various factors, including the indication for extraction, the technique used, and the patient's overall health status 4.
  • Patients with a solitary functioning kidney (SFK) may be at risk of renal injury and should be monitored closely to prevent long-term complications 6.

Pacemaker Extraction Considerations

  • The decision to extract a pacemaker lead should be based on individual patient factors, including the presence of system infection, venous occlusion, or other complications 3, 4.
  • The success rate of lead extraction depends on various factors, including the time from implant, operator experience, and the use of specific tools and techniques 4.
  • Patients with multiple abandoned pacemaker leads, total lead implantations, and procedures of new lead placement should be carefully observed to detect possible pacemaker-associated complications 3.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Is there an adverse outcome from abandoned pacing leads?

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2000

Research

Life with one kidney.

Pediatric nephrology (Berlin, Germany), 2018

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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