What does research say about RestoreX for treating erectile dysfunction, particularly in cases of Peyronie's disease?

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Last updated: June 9, 2025View editorial policy

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From the Guidelines

RestoreX, a penile traction therapy device, is a recommended treatment option for Peyronie's disease and associated erectile dysfunction, as it can reduce penile curvature and improve erectile function with minimal side effects. Research suggests that using RestoreX for 30-90 minutes daily over 3-6 months can reduce penile curvature by 15-20 degrees on average and improve erectile function 1. The recommended regimen typically involves starting with 30-minute sessions and gradually increasing to longer durations as tolerated. RestoreX works by applying gentle, consistent traction to the penis, which helps remodel scar tissue (plaques) responsible for penile curvature and can improve blood flow to erectile tissues.

Some key points to consider when using RestoreX include:

  • Starting with 30-minute sessions and gradually increasing to longer durations as tolerated
  • Using the device for 3-6 months to achieve optimal results
  • Potential side effects include temporary skin irritation or discomfort, which typically resolves with proper device adjustment or brief interruption of treatment
  • RestoreX appears most effective when used during the chronic phase of Peyronie's disease (after 6-12 months from onset) rather than during the acute inflammatory phase

It's worth noting that other treatment options, such as oral non-steroidal anti-inflammatory medications, tunical plication surgery, plaque incision or excision and/or grafting, and penile prosthesis surgery, may also be effective for treating Peyronie's disease and associated erectile dysfunction 1. However, RestoreX is a non-invasive and relatively low-risk treatment option that can be used in conjunction with other therapies or as a standalone treatment. As always, it's essential to discuss the potential benefits and risks of each treatment option with a healthcare provider to determine the best course of treatment for individual patients.

From the Research

Overview of RestoreX Research

  • RestoreX is a novel penile traction therapy device that has been studied for its efficacy in treating erectile dysfunction, particularly in cases of Peyronie's disease 2, 3, 4, 5, 6.
  • The device has been shown to be safe and effective in improving penile length and curvature, as well as erectile function, in men with Peyronie's disease 2, 3.

Efficacy in Peyronie's Disease

  • A randomized, controlled trial found that men with Peyronie's disease who used the RestoreX device for 30 to 90 minutes per day experienced significant improvements in penile length and curvature, as well as erectile function, compared to controls 2.
  • Another study found that the use of RestoreX in combination with collagenase Clostridium histolyticum injections resulted in significantly greater improvements in curvature and length compared to injections alone or with other penile traction therapy devices 5.
  • A review of the literature on penile traction therapy and vacuum erection devices in Peyronie's disease found that RestoreX and other penile traction therapy devices may have a potential role in managing the condition, although more data are needed to fully understand their benefits 6.

Efficacy in Post-Prostatectomy Patients

  • A randomized, controlled trial found that the use of RestoreX in men post-prostatectomy resulted in significant improvements in penile length and erectile function, as well as intercourse satisfaction and overall sexual satisfaction, compared to controls 4.

Safety and Adverse Events

  • The RestoreX device has been shown to be well-tolerated, with only transient and mild adverse events reported in clinical trials 2, 3, 4, 5.
  • The most common adverse events reported were temporary erythema and discomfort, which resolved within minutes 3.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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