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Last updated: June 9, 2025View editorial policy

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Differential Diagnosis for Itchiness on Labia

  • Single most likely diagnosis
    • Eczema/Dermatitis: This is a common condition that can cause itchiness on the labia due to skin irritation or allergic reactions. It's often seen in individuals with a history of atopic diseases.
  • Other Likely diagnoses
    • Vulvovaginal Candidiasis (Yeast Infection): A fungal infection that can cause intense itching, redness, and swelling in the vulvar area, including the labia.
    • Contact Dermatitis: An allergic reaction or irritation from soaps, douches, or other products used in the genital area, leading to itchiness and discomfort.
    • Lichen Sclerosus: A chronic skin condition that can cause itching, pain, and thinning of the skin on the labia and other parts of the vulva.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Malignancy (Vulvar Cancer): Although rare, vulvar cancer can present with persistent itching, and it's crucial to rule out this diagnosis to ensure timely treatment.
    • Herpes Simplex Virus (HSV): Genital herpes can cause itching, along with painful blisters or sores, and has significant implications for sexual health and relationships.
    • Syphilis: A sexually transmitted infection that can cause a variety of symptoms, including itching in the genital area, and has serious consequences if left untreated.
  • Rare diagnoses
    • Lichen Planus: An autoimmune condition that can affect the skin and mucous membranes, including the vulva, causing itching and discomfort.
    • Psoriasis: Although more commonly associated with skin lesions elsewhere on the body, psoriasis can occasionally affect the vulvar area, leading to itching and redness.
    • Keratosis Pilaris: A condition characterized by rough patches on the skin, which can sometimes occur on the labia and cause itching.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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