From the Guidelines
A clot blood patch refers to the use of a patient's own blood to form a clot that seals a site of bleeding, and it is a type of local haemostatic agent used as an adjunct to traditional surgical techniques to obtain haemorrhagic control. The concept of a clot blood patch is based on the principle of using the patient's own blood to form a clot that can seal a site of bleeding, and it is often used in conjunction with other local haemostatic agents such as collagen, gelatine, or cellulose-based products 1. Some of the key characteristics of local haemostatic agents, including clot blood patches, include their ability to trigger platelet aggregation, resulting in clot formation when in contact with a bleeding surface, and their potential to be combined with a pro-coagulant substance to enhance the haemostatic effect 1. The use of clot blood patches and other local haemostatic agents should consider several factors, such as the type of bleeding, severity, coagulation status, and each agent's specific characteristics, and they can be particularly useful when access to the site of bleeding is challenging 1. Some of the benefits of using clot blood patches and other local haemostatic agents include their ability to control bleeding, reduce the need for transfusions, and promote healing of the affected area, and they have been shown to be effective in a variety of clinical settings, including trauma, surgery, and bleeding disorders 1. However, the use of clot blood patches and other local haemostatic agents also carries some risks and potential complications, such as the risk of infection, allergic reactions, and adverse effects on coagulation, and they should be used judiciously and under the guidance of a qualified healthcare professional 1. In terms of the specific composition and mechanism of action of clot blood patches, they typically involve the use of a patient's own blood, which is rich in platelets, fibrinogen, and other coagulation factors, to form a clot that can seal a site of bleeding, and they may be combined with other substances, such as collagen or thrombin, to enhance their haemostatic effect 1. Overall, clot blood patches are an important tool in the management of bleeding and coagulopathy, and they offer a promising approach to controlling bleeding and promoting healing in a variety of clinical settings.
From the Research
Clot Blood Patch
- A clot blood patch is not directly mentioned in the provided studies, however, the concept of achieving hemostasis through various methods is discussed in several studies 2, 3, 4, 5, 6.
- Hemostasis can be achieved through practical and effective systemic or topical approaches, including manual pressure application, electrical tissue cauterization, systemic administration of blood products, and systemic administration or topical application of procoagulation agents 3.
- Topical agents can be effective as adjuncts to aid in hemostasis when bleeding is not controllable with pressure application, vessel ligation, or electrocautery, and include topical gelatins, collagens, oxidized celluloses, thrombin and fibrin sealants, synthetic glues, and glutaraldehyde-based glues 3.
- Mechanical hemostasis techniques, such as injection therapy, sprays/topical agents, electrocautery, and mechanical methods, can be used to control nonvariceal upper gastrointestinal bleeding 4.
- Endoscopic band ligation is a technique that can be used to control nonvariceal upper GI hemorrhage, and has been shown to be efficient, simple, and safe 6.