Is mullein safe and effective for lung support?

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Last updated: June 10, 2025View editorial policy

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From the Guidelines

Mullein is not a recommended treatment for lung support due to limited evidence of its effectiveness and potential risks. When considering the safety and efficacy of mullein for lung support, it is essential to prioritize morbidity, mortality, and quality of life as outcomes. The available evidence does not provide strong support for the use of mullein in lung support.

  • Traditionally, mullein has been used for respiratory conditions, and it contains mucilage and other compounds that may have anti-inflammatory and expectorant properties.
  • However, the evidence for its effectiveness is limited, and there are potential risks associated with its use, such as skin irritation and toxic compounds in the seeds.
  • In contrast, conventional medical treatments for respiratory conditions, such as asthma, COPD, or infections, have a stronger evidence base and are generally considered safer and more effective.
  • The American Thoracic Society and European Respiratory Society statement on pulmonary rehabilitation 1 emphasizes the importance of evidence-based treatments for chronic respiratory disease, and the Chest guideline on symptomatic treatment of cough among adult patients with lung cancer 1 suggests that opioids, such as pholcodine or hydrocodone, may be effective in managing cough, but notes that the evidence is limited.
  • Therefore, it is recommended to prioritize conventional medical treatments over mullein for lung support, and to consult with a healthcare provider before using any herbal remedies, especially for pregnant or breastfeeding women, children, and those with existing medical conditions.

From the Research

Safety and Efficacy of Mullein for Lung Support

  • Mullein, also known as Verbascum thapsus L., has been used for centuries to treat various health conditions, including lung disorders 2, 3.
  • The plant contains a variety of phytoconstituents, such as flavonoids, iridoid, phenylethanoid, and phenylpropanoid glycosides, saponins, as well as vitamin C and minerals, which contribute to its medicinal properties 2.
  • Studies have demonstrated the antiviral, antioxidant, analgesic, sedative, anti-inflammatory, hypnotic, antibacterial, antifungal, and anticancer activities of mullein 2, 4.
  • Mullein has been traditionally used to treat pulmonary problems, inflammatory diseases, asthma, spasmodic coughs, and other respiratory issues 3, 4.
  • While there is limited research on the specific use of mullein for lung support, the available evidence suggests that it may be safe and effective in alleviating respiratory symptoms 3, 4.
  • However, it is essential to note that mullein can interact with certain medications and may not be suitable for everyone, particularly those with certain health conditions or allergies 2, 3.

Potential Benefits for Lung Health

  • Mullein's anti-inflammatory and antioxidant properties may help reduce inflammation and oxidative stress in the lungs, potentially alleviating symptoms of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD) 2, 4.
  • The plant's expectorant properties may also help loosen and clear mucus from the lungs, making it easier to breathe 3, 4.
  • Additionally, mullein's antiviral and antibacterial properties may help protect against respiratory infections, such as the common cold and flu 2, 4.

Comparison with Other Herbal Remedies

  • A systematic review and meta-analysis of herbal medicines for cough found that mullein was not among the most effective herbal remedies, with stronger evidence supporting the use of Andrographis paniculata, ivy/primrose/thyme, and Pelargonium sidoides 5.
  • However, mullein has been traditionally used in combination with other herbs, such as thyme and ivy, to treat respiratory conditions, and may be a useful adjunct therapy 3, 6.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Biological activity of common mullein, a medicinal plant.

Journal of ethnopharmacology, 2002

Research

Herbal Medicine for Cough: a Systematic Review and Meta-Analysis.

Forschende Komplementarmedizin (2006), 2015

Research

Open trial to assess aspects of safety and efficacy of a combined herbal cough syrup with ivy and thyme.

Forschende Komplementarmedizin und klassische Naturheilkunde = Research in complementary and natural classical medicine, 2005

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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