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Last updated: June 10, 2025View editorial policy

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Differential Diagnosis for Back Pain after Eating

  • Single most likely diagnosis
    • Gastroesophageal reflux disease (GERD): Back pain after eating can be a referred pain from the stomach, and GERD is a common condition that can cause stomach discomfort and pain that may radiate to the back.
  • Other Likely diagnoses
    • Peptic ulcer disease: Similar to GERD, peptic ulcers can cause stomach pain that may be referred to the back, especially after eating.
    • Pancreatitis: Inflammation of the pancreas can cause severe back pain, especially after eating, due to the location of the pancreas and its proximity to the spine.
    • Cholecystitis: Inflammation of the gallbladder can cause right upper quadrant pain that may radiate to the back, especially after eating fatty foods.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Myocardial infarction: Although less common, back pain after eating can be a symptom of a heart attack, especially in women, and is a medical emergency.
    • Aortic dissection: Severe back pain after eating can be a symptom of an aortic dissection, which is a life-threatening condition that requires immediate medical attention.
    • Pulmonary embolism: Back pain after eating can be a symptom of a pulmonary embolism, especially if the pain is accompanied by shortness of breath or other respiratory symptoms.
  • Rare diagnoses
    • Pheochromocytoma: A rare tumor of the adrenal gland that can cause back pain, especially after eating, due to the release of catecholamines.
    • Medullary sponge kidney: A rare congenital disorder that can cause back pain, especially after eating, due to the formation of kidney stones.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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