What is the indication for Lidocaine (Lignocaine) Hydrochloride (HCl) 5% jelly (JEL) formulation?

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Last updated: February 24, 2025View editorial policy

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From the Research

Lidocaine HCl 5% jelly formulation is indicated for topical anesthesia to numb the mucous membranes before medical procedures, such as dental procedures, or to relieve pain from minor cuts, burns, or insect bites. The provided evidence does not directly address the indication for Lidocaine HCl 5% jelly formulation. However, based on general medical knowledge, lidocaine is a common local anesthetic used to reduce pain and discomfort during medical procedures. Some key points to consider when using lidocaine HCl 5% jelly formulation include:

  • Apply a thin layer to the affected area as needed, typically 2-3 times daily
  • For medical procedures, apply 15-20 minutes before the procedure starts
  • Do not use on large areas of the body or broken skin without medical supervision
  • The maximum single dose should not exceed 20 grams of the 5% gel (1 gram of lidocaine)
  • Lidocaine works by blocking nerve signals in your body to reduce pain sensation
  • It's essential to avoid getting the gel in your eyes, nose, or mouth
  • If you're using it for a medical procedure, follow your healthcare provider's specific instructions
  • Stop use and seek medical attention if you experience severe burning, stinging, or irritation where you applied the gel, as reported in various studies 1, 2, 3, 4, 5.

In terms of specific medical procedures, a study from 4 compared the efficacy and safety of 2% lidocaine HCl with different epinephrine concentrations for local anesthesia in participants undergoing surgical extraction of impacted mandibular third molars. Although this study does not directly address the indication for Lidocaine HCl 5% jelly formulation, it highlights the importance of considering the concentration and formulation of lidocaine when used for local anesthesia.

Another study from 1 discussed the use of lidocaine-loaded dissolving microneedles for safe local anesthesia on oral mucosa for dental procedures, which may be relevant to the indication for Lidocaine HCl 5% jelly formulation. However, more research is needed to fully understand the efficacy and safety of this specific formulation.

Overall, while the provided evidence does not directly address the indication for Lidocaine HCl 5% jelly formulation, general medical knowledge and related studies suggest that it is used for topical anesthesia to numb the mucous membranes before medical procedures or to relieve pain from minor cuts, burns, or insect bites.

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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