Differential Diagnosis for 35-Year-Old Experiencing Earlier Cycles of Menstruation
Single Most Likely Diagnosis
- Polycystic Ovary Syndrome (PCOS): This condition is a common endocrine disorder among women of reproductive age and can cause irregular menstrual cycles, including more frequent menstruation due to anovulatory cycles or hormonal imbalances.
Other Likely Diagnoses
- Thyroid Disorders: Both hyperthyroidism and hypothyroidism can affect menstrual regularity. Hyperthyroidism, in particular, can lead to more frequent menstrual cycles.
- Stress and Weight Changes: Significant stress or changes in weight can disrupt the normal balance of hormones, leading to changes in menstrual cycle frequency.
- Premature Ovarian Failure (POF): Although less common, POF can cause irregular and more frequent menstrual cycles due to the premature depletion of ovarian follicles.
Do Not Miss Diagnoses
- Pituitary Tumors: Tumors such as prolactinomas can disrupt normal pituitary function, leading to hormonal imbalances that affect menstrual cycles. Early detection is crucial for effective management.
- Endometrial or Ovarian Cancer: Although rare in this age group, any significant change in menstrual pattern warrants investigation to rule out malignancies.
Rare Diagnoses
- Adrenal Disorders: Certain adrenal gland disorders, such as congenital adrenal hyperplasia, can affect hormone production and lead to changes in menstrual cycles.
- Genetic Disorders: Conditions like Turner syndrome or other genetic abnormalities can impact menstrual regularity, though these are typically identified earlier in life.
- Autoimmune Disorders: Certain autoimmune conditions can affect the endocrine system and lead to menstrual irregularities, though these are less common causes of earlier menstrual cycles.