From the Guidelines
Benzodiazepine withdrawal symptoms can be alleviated with supplements such as magnesium aspartate, as suggested by a recent study 1, which should be used in conjunction with a gradual tapering schedule and medical supervision. When considering supplements to alleviate benzodiazepine withdrawal symptoms, it's essential to prioritize those that have been studied in the context of benzodiazepine withdrawal.
- Magnesium aspartate has been investigated as an adjunctive pharmacological intervention to facilitate tapering long-term benzodiazepines 1.
- Other supplements like valerian root, L-theanine, and omega-3 fatty acids may also be beneficial in reducing anxiety and promoting relaxation, although their specific use in benzodiazepine withdrawal is not as well-studied.
- It's crucial to start with low doses and gradually increase as needed, as some individuals may be sensitive during withdrawal.
- A gradual tapering schedule, such as reducing the daily benzodiazepine dose by 25% each week, can help minimize the risk of rebound or withdrawal symptoms 1.
- Non-pharmacological interventions, including education, self-empowerment, and psychosocial support, can also play a significant role in successful benzodiazepine tapering 1.
- Ultimately, any supplement regimen should be personalized and monitored by a healthcare provider to ensure safe and effective management of benzodiazepine withdrawal symptoms.
From the Research
Supplements for Alleviating Benzodiazepine Withdrawal Symptoms
There are no specific supplements mentioned in the provided studies as effective for alleviating benzodiazepine withdrawal symptoms. However, the following medications and strategies have been discussed:
- Adjuvant medication such as antidepressants and propranolol may occasionally be required 2
- Carbamazepine, imipramine, valproate, and trazodone have been beneficial in the management of benzodiazepine discontinuation, but not in decreasing the severity of benzodiazepine withdrawal 3
- Antidepressants can help if the patient is depressed before withdrawal or develops a depressive syndrome during withdrawal 4
- Carbamazepine was the only drug that appeared to have any useful adjunctive properties for assisting in the discontinuation of benzodiazepines 4
- Valproate and carbamazepine have been used in the treatment of benzodiazepine withdrawal 5
Strategies for Benzodiazepine Withdrawal
Some strategies for benzodiazepine withdrawal include:
- Gradual dosage reduction and psychological support 2
- Multifaceted prescription strategies, gradual dose reduction, standardized letters, standardized counseling, pharmacotherapy, and cognitive behavioral psychotherapy 6
- A stepwise approach to discontinuing benzodiazepines 3
- Tapering the medication, with the aim of withdrawal in less than 6 months 4
- Substitution of diazepam for another benzodiazepine can be helpful, at least logistically, as diazepam is available in a liquid formulation 4
- Psychological interventions, such as simple support, counseling, and expert cognitive-behavioral therapy (CBT) 4