From the FDA Drug Label
For best results, apply 1 mL with applicator 2 times a day directly onto the scalp in the hair loss area. The starting dose for minoxidil (5% solution) is 1 mL, applied twice a day.
- The dose should be applied directly onto the scalp in the hair loss area.
- Using more or using more often will not improve results 1.
From the Research
The starting dose for minoxidil in the treatment of androgenetic alopecia is typically the 2% solution for women and the 5% solution for men, applied twice daily to the affected areas of the scalp. Each application should use approximately 1 mL of solution, gently massaged into the scalp, and allowed to dry completely before styling hair. Treatment should be continued consistently as minoxidil requires regular use for at least 4 months before noticeable results may appear, and benefits are maintained only with continued application. If treatment is discontinued, any new hair growth will likely be lost within 3-4 months. The 2% solution is generally recommended for women initially due to a lower risk of side effects such as unwanted facial hair growth, while men typically start with the stronger 5% formulation for more effective results. Minoxidil works by prolonging the growth phase of hair follicles and increasing follicular size through vasodilation and enhanced blood flow to the scalp, though the exact mechanism is not fully understood 2.
Some key points to consider when using minoxidil for androgenetic alopecia include:
- The 5% solution and foam were not significantly different in efficacy from the 2% solution 2
- Topical minoxidil causes hair regrowth in both frontotemporal and vertex areas 2
- Oral and sublingual minoxidil are not FDA approved but may be safe and effective for certain cases of hair loss 2
- The association of 5% minoxidil with other treatments, such as topical finasteride, may show improved clinical efficacy compared to monotherapy 3
It's essential to note that while minoxidil is effective for treating androgenetic alopecia, it may not work for everyone, and results can vary. Regular use and patience are necessary to achieve optimal results. As with any medication, it's crucial to follow the recommended dosage and application instructions to minimize potential side effects. Consultation with a healthcare professional is recommended before starting minoxidil treatment, especially for women and individuals with certain medical conditions.