What is the role of BPC (Body Protection Compound) 157 in the treatment of plantar fasciitis?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: June 12, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

BPC-157 is not a recommended treatment for plantar fasciitis due to the lack of standardized production, quality control, and established safety profiles, and traditional treatments should be prioritized. The current evidence for BPC-157 in treating plantar fasciitis is limited and mostly anecdotal or from animal studies. Traditional treatments such as rest, stretching, proper footwear, physical therapy, and anti-inflammatory medications remain the standard first-line approaches for plantar fasciitis, as recommended by the American College of Foot and Ankle Surgeons 1.

Treatment Options

  • Rest and decreased activity to reduce pressure on the affected area
  • Stretching exercises to improve flexibility and reduce tension
  • Proper footwear, including open-backed shoes and orthoses, to reduce pressure and provide support
  • Anti-inflammatory medications to reduce pain and inflammation
  • Physical therapy to improve strength and flexibility

Alternative Treatments

If no improvement occurs after six weeks, referral to a podiatric foot and ankle surgeon is appropriate, and additional treatments may include:

  • Customized orthotic devices
  • Night splinting
  • Limited corticosteroid injections
  • Casting or use of a fixed-ankle walker-type device during activity
  • Surgery (plantar fasciotomy) or extracorporeal shock wave therapy in severe cases

It's essential to consult with a healthcare provider before considering any treatment, especially experimental peptides like BPC-157, to ensure the best possible outcome and minimize potential risks. The American College of Foot and Ankle Surgeons recommends a step-wise approach to treatment, starting with conservative measures and progressing to more invasive options only if necessary 1.

From the Research

BPC 157 and Plantar Fasciitis

  • There is no direct evidence in the provided studies regarding the role of BPC 157 in the treatment of plantar fasciitis.
  • The studies focus on various treatments for plantar fasciitis, including conservative management, corticosteroid injections, and orthotics 2, 3, 4, 5, 6.
  • Plantar fasciitis is a common cause of heel pain, and its treatment often involves a combination of rest, activity modification, ice massage, oral analgesics, and stretching techniques 2, 4.
  • Corticosteroid injections combined with controlled training have been shown to be an effective treatment for plantar fasciitis 5.
  • Orthotics, both prefabricated and custom fitted, can reduce pain and improve function in adults with acute plantar fasciitis 6.

Treatment Options for Plantar Fasciitis

  • Conservative treatments, such as rest, activity modification, and stretching, are often recommended as the first line of treatment 2, 4.
  • Corticosteroid injections can be used to treat recalcitrant plantar fasciitis, and combining them with controlled training has been shown to be effective 5.
  • Orthotics can be used to reduce pain and improve function in adults with acute plantar fasciitis 6.
  • Extracorporeal shock wave therapy and plantar fasciotomy may be considered for patients with chronic recalcitrant plantar fasciitis 2, 4.

Diagnosis and Risk Factors

  • Plantar fasciitis is primarily diagnosed based on history and physical examination 2, 4.
  • Risk factors for developing plantar fasciitis include obesity, excessive foot pronation, excessive running, and prolonged standing 2, 3, 4.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Diagnosis and treatment of plantar fasciitis.

American family physician, 2011

Research

Plantar Fasciitis: Diagnosis and Conservative Management.

The Journal of the American Academy of Orthopaedic Surgeons, 1997

Research

Plantar Fasciitis.

American family physician, 2019

Research

Corticosteroid injection is the best treatment in plantar fasciitis if combined with controlled training.

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2019

Research

Orthotics Compared to Conventional Therapy and Other Non-Surgical Treatments for Plantar Fasciitis.

The Journal of the Oklahoma State Medical Association, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.