What is the greatest risk factor for frostbite in a 54-year-old man with diabetes (Diabetes Mellitus), hyperlipidemia, hypertension, and hypothyroidism, who develops redness and stinging of the fingers and toes after working outdoors for several hours during a winter storm?

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Last updated: February 25, 2025View editorial policy

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From the Guidelines

The greatest risk factor for frostbite in this 54-year-old man is his diabetes, as it significantly impairs peripheral circulation and causes neuropathy, reducing sensation in the extremities. Diabetes, as noted in the 2024 American Heart Association and American Red Cross guidelines for first aid 1, makes individuals particularly vulnerable to cold injuries due to impaired sensation and circulation. The patient's other medical conditions, including hyperlipidemia, hypertension, and hypothyroidism, further increase his risk by potentially worsening vascular disease and reducing the body's ability to maintain temperature in cold environments.

Some key points to consider in this patient's case include:

  • The patient's occupation and environmental exposure to cold temperatures during the winter storm directly contributed to his risk of developing frostbite.
  • The symptoms of redness and stinging in the fingers and toes are early warning signs of frostbite, and immediate treatment should focus on gentle rewarming of affected areas, pain management, and prevention of further tissue damage 1.
  • Long-term management should include better glycemic control and appropriate protective measures during cold weather work to prevent future episodes of frostbite.
  • Additionally, the use of NSAIDs, such as ibuprofen, may be recommended to decrease the production of prostaglandins and thromboxanes that can cause vasoconstriction, dermal ischemia, and further tissue damage in frostbite, as suggested by the 2024 American Heart Association and American Red Cross guidelines for first aid 1.

From the Research

Risk Factors for Frostbite

The greatest risk factor for frostbite in a 54-year-old man with diabetes, hyperlipidemia, hypertension, and hypothyroidism, who develops redness and stinging of the fingers and toes after working outdoors for several hours during a winter storm, includes:

  • Predisposing individual factors such as poor circulation in peripheral parts of the body, which can be exacerbated by diabetes and hypertension 2
  • Environmental factors like low temperatures, high wind speeds, and moisture, which can increase the risk of frostbite 3, 4
  • Behavioral factors, including inadequate clothing, fatigue, and dehydration, which can contribute to heat loss and increase the risk of frostbite 2

Physiological Factors

Physiological factors that may contribute to the risk of frostbite in this individual include:

  • Decreased heat production due to hypothyroidism, which can reduce the body's ability to maintain core temperature in cold environments 2
  • Decreased insulation of clothing, which can increase heat loss and contribute to frostbite 2
  • Increased susceptibility to cold due to underlying medical conditions, such as diabetes and hypertension, which can affect blood flow and circulation to extremities 2

Prevention and Treatment

Prevention of frostbite is crucial, and measures such as:

  • Recognizing cold risks and taking steps to mitigate them 2, 4
  • Wearing proper clothing, including layers and protective gear for extremities 4
  • Staying hydrated and avoiding fatigue 2
  • Avoiding repeated freeze/thaw cycles, which can cause further injury 5, 4 can help reduce the risk of frostbite. If frostbite occurs, treatment involves rapid rewarming in a warm environment, and thrombolytics may be beneficial in the early treatment of severe frostbite 5, 4

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Predisposing factors and prevention of frostbite.

International journal of circumpolar health, 2000

Research

Critical care for frostbite.

Critical care nursing clinics of North America, 2012

Research

Frostbite: Pathophysiology, Epidemiology, Diagnosis, Treatment, and Prevention.

Journal of special operations medicine : a peer reviewed journal for SOF medical professionals, 2020

Research

Frostbite: prevention and initial management.

High altitude medicine & biology, 2013

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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