Azithromycin 1.5% Ophthalmic Solution Dispensed Volume
The dispensed volume for azithromycin 1.5% ophthalmic solution is 2.5 mL per bottle 1.
Product Specifications
The FDA-approved azithromycin 1.5% ophthalmic formulation (marketed as Azyter® in some regions) comes in a 2.5 mL sterile bottle 1. This volume is specifically designed to provide sufficient medication for the complete treatment course.
Storage and Shelf Life Considerations
Important practical points about this formulation:
- Before opening: Store refrigerated at 36°F to 46°F (2°C to 8°C)
- After opening: Can be stored at room temperature or refrigerated between 36°F to 77°F (2°C to 25°C)
- Discard after 14 days of opening the bottle 1
Treatment Duration Context
The 2.5 mL volume provides adequate supply for the standard treatment regimen:
- Days 1-2: 1 drop twice daily (8-12 hours apart)
- Days 3-7: 1 drop once daily
- Total: 9 drops per affected eye 1
This means a single 2.5 mL bottle contains sufficient medication for bilateral treatment with appropriate reserve, accounting for potential missed drops or spillage during administration.
Clinical Relevance
The 2.5 mL dispensing volume represents a practical formulation size that balances adequate treatment supply with the 14-day post-opening stability limitation, minimizing waste while ensuring treatment completion 1.