From the Guidelines
To relieve constipation with laxatives, start with gentle options like osmotic laxatives such as polyethylene glycol (MiraLAX), taken as 17g dissolved in 8oz of water once daily, or magnesium hydroxide (Milk of Magnesia), 30-60ml at bedtime, as recommended by recent guidelines 1. These work by drawing water into the intestines to soften stool. If needed, stimulant laxatives like bisacodyl (Dulcolax) 5-10mg or senna (Senokot) 8.6-17.2mg can provide faster relief within 6-12 hours by increasing intestinal contractions. Stool softeners such as docusate sodium (Colace) 100mg once or twice daily may help if stools are hard. For occasional use, suppositories or enemas can provide same-day relief. While using laxatives, drink plenty of water, increase dietary fiber gradually, and stay physically active. Most laxatives should be used short-term (less than 7 days) to avoid dependence. If constipation persists beyond a week, recurs frequently, or is accompanied by concerning symptoms like blood in stool or severe pain, consult a healthcare provider as this could indicate an underlying condition requiring different treatment, as suggested by various studies 1.
Some key points to consider when using laxatives include:
- Starting with gentle options and gradually increasing the strength or dosage as needed
- Drinking plenty of water to help soften stool and prevent dehydration
- Increasing dietary fiber gradually to help promote regular bowel movements
- Staying physically active to help stimulate bowel movements
- Avoiding long-term use of laxatives to prevent dependence
- Consulting a healthcare provider if constipation persists or is accompanied by concerning symptoms.
It's also important to note that different types of laxatives may be more or less effective for different individuals, and some may have side effects or interact with other medications, as discussed in the studies 1. Therefore, it's essential to follow the recommended guidelines and consult a healthcare provider if you have any questions or concerns about using laxatives to relieve constipation.
From the FDA Drug Label
USE • relieves occasional constipation (irregularity) • generally produces a bowel movement in 1 to 3 days To relieve constipation using laxatives, you can use polyethylene glycol (PO), which generally produces a bowel movement in 1 to 3 days 2.
- Do not use laxative products for longer than one week unless directed by a doctor 3.
- If you need to use a laxative for more than one week, stop use and ask a doctor 4.
From the Research
Using Laxatives to Relieve Constipation
To clean out with laxatives (lax) for constipation, it's essential to understand the different types of laxatives and their effectiveness.
- Osmotic laxatives, such as polyethylene glycol, are commonly used to treat constipation 5, 6, 7, 8.
- Stimulant laxatives, like senna, can also be effective in relieving constipation 6, 9, 8.
- Fiber supplements, fruits, and magnesium-based products have moderate evidence supporting their use 6, 8.
Choosing the Right Laxative
When selecting a laxative, consider the following:
- Polyethylene glycol and senna have good evidence supporting their use as first-line laxatives 6, 8.
- Senna may be more effective than polyethylene glycol in certain cases, such as in children with anorectal malformations 9.
- It's crucial to follow the recommended dosage and consult a healthcare provider if symptoms persist or worsen.
Safety and Adverse Effects
Laxatives are generally well-tolerated, but common adverse effects include: