From the Guidelines
Mirilax can be considered for children as young as 6 months of age, but there is no strong evidence to support its use in children under 1 year of age, and it's most commonly recommended for children 1 year and older and adults of all ages. For children under 17, it's best to consult with a pediatrician before use to determine the appropriate dosage. The standard adult dose is 17 grams (about 1 heaping tablespoon) dissolved in 8 ounces of water once daily. Mirilax works by drawing water into the colon, softening stool and increasing bowel movements without causing cramping. It typically takes 1-3 days to produce a bowel movement. Mirilax is generally considered safe for longer-term use because it's not absorbed into the bloodstream and works locally in the digestive tract. However, it should not replace addressing underlying causes of constipation such as inadequate fluid intake, lack of dietary fiber, or insufficient physical activity. According to the US multi-society task force on colorectal cancer 1, there is no specific recommendation for the use of Mirilax in children, but it does recommend that NaP preparations should not be used in children younger than age 12. Another study also recommends that NaP should not be used in children younger than 12 years of age 1.
Some key points to consider when using Mirilax in children include:
- Consulting with a pediatrician before use to determine the appropriate dosage
- Monitoring for signs of dehydration or electrolyte imbalance
- Avoiding use in children with significant comorbidities or those at high risk for dehydration or electrolyte imbalance
- Using the lowest effective dose for the shortest duration necessary. It's also important to note that Mirilax is not absorbed into the bloodstream and works locally in the digestive tract, making it a relatively safe option for longer-term use 1.
From the FDA Drug Label
children 16 years of age or under: ask a doctor adults and children 17 years of age and older: Mirilax, also known as polyethylene glycol (PO), can be considered for use in individuals 17 years of age and older without consulting a doctor. For children 16 years of age or under, it is recommended to ask a doctor before use 2.
From the Research
Miralax Age Consideration
- The provided studies do not specifically mention the age at which Miralax can be considered for use.
- However, the studies discuss the use of polyethylene glycol (PEG) 3350, which is the active ingredient in Miralax, in children with constipation 3, 4, 5, 6.
- According to the studies, PEG 3350 is considered a safe and effective treatment for pediatric constipation, but the exact age range for its use is not specified 3, 4.
- It is recommended to consult a healthcare professional for guidance on the use of Miralax in children, as they can provide personalized advice based on the child's age, medical history, and individual needs.
Key Findings
- PEG 3350 is a commonly used and effective treatment for constipation in children 3, 4, 5, 6.
- Senna, a stimulant laxative, is also considered effective for treating constipation in children, particularly those with anorectal malformations 4.
- The use of PEG 3350 and senna is supported by good evidence, while other agents such as psyllium, magnesium salts, and fruit-based laxatives have moderate evidence supporting their use 5, 6.