I cannot provide case report links as requested
The evidence provided does not contain URLs or links to case reports of concurrent lung mass and brain mass. However, I can identify several case reports described in the research evidence that document this clinical scenario:
Available Case Reports (Without Links)
Recent Case Reports Identified:
Lung Adenocarcinoma with Concurrent Brain and Leptomeningeal Metastasis 1
- EGFR-mutant NSCLC patient with simultaneous brain parenchymal metastasis (BPM) and leptomeningeal metastasis (LM)
- Patient had bone metastases, LM, and BPM concurrently
- Published in Frontiers in Oncology (2026)
Sarcomatoid Carcinoma with Concurrent Pulmonary and Brain Metastasis 2
- 55-year-old male with pulmonary sarcomatoid carcinoma
- Presented with solitary left frontal brain metastasis and incidentally discovered breast metastasis
- Published in Radiology Case Reports (2025)
Lung Carcinoma Mimicking Glioma 3
- 73-year-old male with primary bronchogenic carcinoma and brain metastasis
- Initially misdiagnosed as high-grade glioma
- Published in Cureus (2024)
Primary Pulmonary Sarcomatous Cancer with Brain Metastasis 4
- 79-year-old female with 6.8 x 3.5 cm right upper lobe lung mass
- Developed multiple bilateral brain metastases shortly after diagnosis
- Published in Cureus (2023)
Solitary Brain Metastasis from Primary Lung Cancer 5
- 59-year-old male presenting with neurological symptoms
- Solitary brain lesion with concurrent primary lung tumor
- Published in International Journal of Surgery Case Reports (2023)
Clinical Context from Guidelines
The guidelines emphasize that synchronous presentation of lung and brain masses is well-recognized 6:
- Lung cancer accounts for approximately 50% of all brain metastases 7
- 20-40% of lung cancer patients develop brain metastases 7
- Synchronous presentation (brain and lung masses discovered together) carries a worse prognosis with median survival of only 3 months 6
- Exception: Patients with a single brain lesion and single peripheral lung lesion that are both completely resectable can have surprisingly good outcomes if the lung lesion shows no nodal positivity 6
I cannot provide direct links to these case reports, but the reference information above should allow you to locate them through medical databases like PubMed using the journal names, years, and titles provided.