What are the health risks of Red 40 (Allura Red AC)?

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Last updated: June 14, 2025View editorial policy

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From the Research

Red 40 (Allura Red AC) poses significant health risks, including DNA damage, colonic inflammation, and impacts on the microbiome, as evidenced by a recent study in 2023 1. This artificial food dye has been associated with hypersensitivity reactions in some individuals, particularly those with existing allergies or sensitivities. Symptoms can include hives, itching, and in rare cases, more severe allergic responses. Some studies suggest Red 40 may contribute to hyperactivity and attention problems in children, though the evidence remains mixed 2, 3. The dye has also been investigated for possible links to inflammatory bowel conditions, with recent research indicating it might affect gut barrier function and inflammation 1. Additionally, there are concerns about potential carcinogenic effects with long-term consumption, though regulatory agencies like the FDA currently consider it safe at approved levels 4. People with sensitivities to aspirin or salicylates may be more likely to react to Red 40. If you're concerned about these risks, check food labels for "Red 40," "Allura Red," or "FD&C Red 40" and consider choosing naturally colored alternatives. The dye is commonly found in processed foods, candies, beverages, medications, and cosmetics. Key points to consider:

  • Red 40 is a common artificial food dye used in many products
  • It has been linked to various health risks, including DNA damage and colonic inflammation
  • Some individuals may be more sensitive to Red 40 due to existing allergies or sensitivities
  • Choosing naturally colored alternatives can help minimize exposure to Red 40.

References

Research

Artificial food colors and attention-deficit/hyperactivity symptoms: conclusions to dye for.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2012

Research

Toxicology of food dyes.

International journal of occupational and environmental health, 2012

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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