From the Guidelines
The most effective treatment for juvenile adolescent stretch marks is the combination of autologous platelet concentrates (APCs) with other modalities such as microneedling, intradermal RF, carboxytherapy, pulsed dye laser (PDL), or CO2 laser, as it has been shown to significantly improve the appearance of stretch marks and histopathological outcomes. When considering treatment options, the following modalities can be used:
- APCs combined with CO2 laser, which has been shown to be more promising and have better patient satisfaction and fewer side effects compared to other combinations 1
- Microneedling with APCs, which can stimulate collagen production and improve skin texture
- Intradermal RF with APCs, which can help improve skin elasticity and appearance
- Carboxytherapy with APCs, which can increase blood flow and reduce the appearance of stretch marks
- PDL or CO2 laser treatments with APCs, which can promote collagen remodeling and improve skin texture It is essential to note that early intervention, when stretch marks are still in the striae rubra stage, yields better outcomes than treating them in the striae alba stage. Maintaining proper hydration and following a balanced diet rich in vitamins C, E, zinc, and protein can also support skin health during treatment 1. Key considerations for treatment include:
- Starting treatment early for better outcomes
- Combining treatments for superior results
- Maintaining proper hydration and a balanced diet to support skin health
- Being patient, as most treatments require several weeks to months before visible improvement occurs The use of APCs in combination with other modalities has been shown to improve histopathological outcomes, including epidermal atrophy, increase in epidermal thickness, and an increase in rete ridges formation with a decrease in perivascular inflammatory infiltrate 1.
From the Research
Treatment Options for Juvenile Adolescent Striae
The treatment of juvenile adolescent striae, also known as stretch marks, is a common concern due to their cosmetic impact. Several treatment options are available, although none have been proven to be 100% effective 2.
Topical Treatments
- Topical tretinoin (retinoic acid) has been shown to improve the appearance of early stretch marks, with significant improvements in severity scores and a decrease in mean length and width of stretch marks 3.
- Other topical treatments, such as glycolic acid and ascorbic acid, have also been used to treat stretch marks, although their effectiveness is variable 4.
Laser and Light Therapies
- Various lasers, including carbon dioxide, Er:YAG, diode, Q-switched Nd:YAG, pulse dye, and excimer laser, have been used to treat stretch marks, with variable success 4.
- Other devices, such as radiofrequency and phototherapy, have also been used to treat stretch marks 4.
Other Therapies
- Platelet-rich plasma, chemical peeling, microdermabrasion, needling, carboxytherapy, and galvanopuncture are other therapies that have been used to treat stretch marks, although their effectiveness is variable 4.
- Understanding the molecular and cellular mechanisms of stretch marks is crucial for the development of new and effective treatments 5.