From the Research
Topical Dimethylaminoethanol (DMAE) works in skincare primarily by stabilizing cell membranes and potentially increasing acetylcholine levels in the skin, with the most recent and highest quality study suggesting its role in increasing skin firmness and potentially improving underlying facial muscle tone 1. The mechanism of action of topical DMAE in skin care is multifaceted, involving several key processes:
- Stabilization of cell membranes, which can lead to improved skin hydration and reduced inflammation
- Potential increase in acetylcholine levels, which may contribute to the tightening of skin and improvement in facial muscle tone
- Antioxidant properties, helping to protect the skin from free radical damage
- Possible reduction in the accumulation of lipofuscin deposits, which are associated with aging skin Key points to consider when using DMAE products include:
- Typical concentrations of 3-5% in over-the-counter products
- Application once or twice daily to clean skin, typically as a serum or cream
- Awareness that the immediate tightening effect is temporary, with consistent use over weeks to months necessary for cumulative benefits
- Potential for mild redness or irritation, particularly when first using DMAE products, which can be mitigated by starting with lower concentrations and gradually increasing frequency It is essential to note that while DMAE has shown promise in skin care, its mechanisms of action are not yet fully elucidated, and further studies are needed to evaluate its relative efficacy compared to other skin-care regimens 1.