There are no official guidelines to assist in answering this question. I will search for relevant research papers instead.
The FDA Drug Labels for magnesium sulfate (IV) do not address this question.
From the Research
Magnesium Sulfate Dosage
To increase serum magnesium levels by 0.7 mg/dL in a patient with hypomagnesemia, the required dose of magnesium sulfate is not explicitly stated in the provided studies. However, some studies provide information on the dosage of magnesium sulfate used in different clinical scenarios:
- A study on the treatment of acute migraine attacks used 1 g of intravenous magnesium sulfate 1.
- A study on the influence of hypermagnesemia on serum calcium and parathyroid hormone levels used intravenous magnesium sulfate to achieve a serum magnesium level of 6.1 +/- 0.4 mg per deciliter 2.
- A study on mononuclear blood cell magnesium content and serum magnesium concentration in critically ill hypomagnesemic patients used 0.5 and 0.75 mmol/kg of intravenous MgSO4 3.
Key Findings
Some key findings from the studies include:
- The dosage of magnesium sulfate used in the studies ranged from 0.5 to 0.75 mmol/kg 3 to 1 g 1.
- The increase in serum magnesium levels achieved with these dosages is not explicitly stated in terms of a 0.7 mg/dL increase.
- The studies suggest that magnesium sulfate can be effective in increasing serum magnesium levels, but the optimal dosage for a specific increase in serum magnesium levels is not clear.
Considerations
When considering the dosage of magnesium sulfate, it is essential to take into account the patient's renal function, as magnesium is excreted by the kidneys 4. Additionally, the dosage should be tailored to the individual patient's needs, and serum magnesium levels should be monitored to avoid hypermagnesemia 2.