From the Research
Muscle twitches caused by high-dose vitamin B6 supplementation typically resolve within 2-6 weeks after discontinuation, though in some cases they may persist for several months. The duration of symptoms depends on several factors including how long you took high doses, the amount you were taking, and your individual metabolism 1. Vitamin B6 toxicity occurs because excessive amounts can damage nerve tissue, leading to peripheral neuropathy symptoms like muscle twitches, tingling, and numbness. While recovering, maintain a balanced diet without additional B6 supplements and stay hydrated to help your body clear the excess vitamin. Some key points to consider:
- High doses of vitamin B6 can cause severe neurological troubles, including peripheral neuropathy 2
- The amount of vitamin B6 in supplements can vary, and even low doses can potentially cause toxicity in some individuals 3
- Discontinuation of high-dose vitamin B6 supplements can lead to improved symptoms, but the recovery time may vary 1
- If muscle twitches persist beyond 2-3 months after discontinuation, consult a healthcare provider as this could indicate another underlying condition or severe B6 toxicity that may require medical intervention. It's also important to note that the safe upper limit for vitamin B6 intake is set at 100 mg per day, and intakes above 1000 mg per day can cause neuropathy 4. In extreme cases, even higher doses can lead to severe sensorimotor neuropathy 5.