What is the efficacy and safety of Maca (Gelatinized Maca) for managing perimenopause symptoms?

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Last updated: June 22, 2025View editorial policy

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From the Research

Gelatinized maca may be considered as a potential treatment option for managing perimenopause symptoms, particularly hot flashes, mood disturbances, and sexual dysfunction, due to its adaptogenic properties and ability to support hormonal balance. The most recent and highest quality study, 1, published in 2021, demonstrated the safety and effectiveness of Lepidium peruvianum (maca) in managing menopausal-related symptoms, including hot flashes, night sweats, anxiety, and mood changes. Key points to consider when using gelatinized maca for perimenopause symptoms include:

  • A typical dosage ranges from 1,500-3,000 mg daily, taken in divided doses with meals, with benefits potentially appearing after 6-12 weeks of consistent use.
  • Gelatinized maca is generally considered safe for most women, with mild digestive upset being the most common side effect.
  • The proposed mechanism involves maca's adaptogenic properties and its ability to support hormonal balance without containing plant estrogens.
  • Maca contains unique compounds called macamides and macaenes that may influence the endocrine system, though it doesn't directly increase estrogen levels.
  • Before starting maca supplementation, consult with a healthcare provider, especially if you have thyroid conditions, hormone-sensitive conditions, or are taking medications, as maca may interact with hormone therapies or thyroid medications. It is essential to note that while the evidence is promising, it is still limited, and more research is needed to fully understand the effects of gelatinized maca on perimenopause symptoms. Additionally, other studies, such as 2, 3, 4, and 5, provide further insight into the potential benefits and limitations of using gelatinized maca for perimenopause symptoms, but the most recent and highest quality study, 1, should be prioritized when making treatment decisions.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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