From the Research
Bicep tendon rupture is associated with Marfan syndrome, a genetic disorder that affects the body's connective tissue and can lead to cardiovascular complications, including aortic aneurysms and dissections. Patients with Marfan syndrome have a higher risk of experiencing bicep tendon ruptures due to the systemic nature of the disorder, which can affect multiple systems of the body, including the skeletal, ocular, and cardiovascular systems 1. The connection between Marfan syndrome and bicep tendon rupture stems from the disorder's impact on connective tissue, which can lead to tendon weakness and increased risk of rupture.
Some key points to consider:
- Marfan syndrome is a heritable connective tissue disorder that affects multiple systems of the body, including the cardiovascular system 2.
- Aortic root dilatation is a common cardiovascular manifestation of Marfan syndrome, and can lead to aortic dissection and rupture 3.
- The natural history of aortic root aneurysms in Marfan syndrome patients is characterized by a faster expansion rate compared to non-MFS individuals, with aortic root diameter having a significant impact on the yearly risk of developing aortic complications 4.
- While other vascular complications, such as those seen in Ehlers-Danlos syndrome, can also increase the risk of tendon rupture, Marfan syndrome is a specific disorder that has been linked to bicep tendon rupture due to its impact on connective tissue 5.
In terms of morbidity, mortality, and quality of life, it is essential to prioritize the diagnosis and management of Marfan syndrome in patients with bicep tendon rupture, as prompt medical evaluation and treatment can help prevent further cardiovascular complications and improve outcomes. The most recent and highest quality study on this topic is not directly available, but based on the available evidence, Marfan syndrome is the most likely heart disease associated with bicep tendon rupture.