From the Research
Pyrroloquinoline Quinone (PQQ) is considered safe for most adults when taken as a supplement at typical doses of 10-20 mg per day, with minimal side effects reported in humans, as supported by recent studies such as 1 and 2. The safety profile of PQQ is well-established, with no reported toxicity or genotoxicity in various studies, making it a safe nutritional supplement. Some users may experience mild digestive discomfort, headaches, or fatigue when first starting supplementation, but these effects are typically temporary and resolve on their own. PQQ is naturally found in small amounts in foods like kiwi, green peppers, and parsley, and functions as a redox cofactor and antioxidant in the body. Key benefits of PQQ supplementation include:
- Improvements in cardiovascular health
- Enhanced cognitive function
- Weight management
- Improved insulin sensitivity
- Prevention of metabolic syndromes It is essential to consult with a healthcare provider before starting PQQ supplements, especially if you have existing health conditions, are pregnant or nursing, or are taking medications that might interact with supplements. Starting with a lower dose (around 10 mg daily) and monitoring for any adverse reactions is also recommended. Overall, the current evidence suggests that PQQ is a safe and potentially beneficial supplement for overall health and well-being, as noted in studies such as 1 and 2.