From the FDA Drug Label
The FDA drug label does not answer the question.
From the Research
Topical vitamin E is a valuable addition to skin care regimens, particularly when combined with hydroquinone or kojic acid for hyperpigmentation, due to its antioxidant properties and ability to enhance treatment effectiveness while reducing irritation. As a potent antioxidant, vitamin E (tocopherol) helps neutralize free radicals that damage skin cells, providing protection against UV radiation and environmental pollutants 1. When combined with hyperpigmentation treatments like hydroquinone (typically used at 2-4% concentration) or kojic acid (usually at 1-2%), vitamin E enhances their effectiveness while reducing potential irritation. The benefits of topical vitamin E in skin care regimens include:
- Enhancing the effectiveness of hyperpigmentation treatments
- Reducing potential irritation associated with hydroquinone or kojic acid
- Providing antioxidant protection against UV radiation and environmental pollutants
- Improving skin texture and reducing fine lines when used in anti-aging formulations
- Promoting collagen production and maintaining moisture in the skin
- Soothing irritated skin and supporting the healing process with its anti-inflammatory properties. For optimal results, apply these combination products once or twice daily to affected areas after cleansing, and consider starting with lower concentrations and gradually increasing usage to minimize potential irritation, as suggested by studies on hydroquinone and kojic acid 2, 3, 4, 5. Most people see noticeable improvements in skin tone and texture after 8-12 weeks of consistent use.