From the Research
It is generally safe to fly while taking Eliquis (apixaban), but consultation with a healthcare provider before traveling is recommended. Eliquis is an anticoagulant medication that helps prevent blood clots, and in most cases, continuing this medication during air travel is recommended since flying itself can increase the risk of blood clots due to prolonged immobility 1. When flying while on Eliquis, it is essential to carry the medication in carry-on luggage along with a copy of the prescription or a doctor's note explaining the need for the medication.
To minimize risks, several precautions can be taken:
- Stay well-hydrated during the flight
- Move around the cabin when possible (at least every 2 hours)
- Perform simple leg exercises while seated
- Wear compression stockings if recommended by a doctor 1 These precautions help further reduce the risk of developing blood clots during air travel. Eliquis has a relatively short half-life, so maintaining the regular dosing schedule is important even across time zones. If travel crosses multiple time zones, asking a doctor for specific instructions on how to adjust the dosing schedule is advisable.
The safety and efficacy of apixaban have been demonstrated in various studies, including its use in patients with venous thromboembolism 2 and nonvalvular atrial fibrillation 3. More recent studies, such as the one published in 2022, have also shown apixaban to be safe and effective in post-bariatric patients for thromboprophylaxis 4. However, it's crucial to consider individual patient factors and consult with a healthcare provider before flying, especially for those with underlying pulmonary disease, as hypoxia during air travel can be a significant concern 5.
Given the most recent and highest quality evidence, consulting with a healthcare provider before traveling while on Eliquis is crucial to ensure safe air travel and to discuss any necessary precautions or adjustments to the medication regimen 1.