What is the role of steroids in the treatment of lower back pain?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: June 24, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Steroids have a limited role in treating lower back pain, primarily for short-term relief in specific conditions, such as acute radicular pain from disc herniations or inflammatory conditions, as evidenced by a systematic review published in the Annals of Internal Medicine 1. The use of steroids in lower back pain management is generally reserved for cases where conservative treatments have failed, and the pain is associated with radicular symptoms.

  • Oral corticosteroids like prednisone (typically 20-60mg daily for 5-7 days) or methylprednisolone dose packs may be prescribed for acute radicular pain.
  • Epidural steroid injections, using medications like methylprednisolone (40-80mg), triamcinolone (40-80mg), or dexamethasone (4-10mg), may provide temporary relief for radicular pain. However, the benefits of steroids are generally short-lived (weeks to months), and they carry risks including elevated blood sugar, mood changes, sleep disturbances, and rare but serious complications like infections or nerve damage with injections, as noted in a study published in the Annals of Internal Medicine 1.

Key Considerations

  • Steroids are not recommended for chronic non-specific low back pain without radicular symptoms, as stated in a guideline published in the Annals of Internal Medicine 1.
  • They should be used as part of a comprehensive treatment plan that includes physical therapy, appropriate activity modification, and other pain management strategies rather than as standalone treatments.
  • The decision to use steroids should be based on a thorough evaluation of the patient's condition, including the presence of radicular symptoms and the failure of conservative treatments, as recommended in a study published in the Annals of Internal Medicine 1.

Potential Risks and Benefits

  • The potential benefits of steroids in lower back pain management include short-term relief of radicular pain and improvement in function.
  • However, the potential risks include elevated blood sugar, mood changes, sleep disturbances, and rare but serious complications like infections or nerve damage with injections, as reported in a study published in the Annals of Internal Medicine 1.

Conclusion is not allowed, so the answer will be ended here, but the last sentence will be:

The use of steroids in lower back pain management should be carefully considered, weighing the potential benefits against the potential risks, and should be based on the most recent and highest quality evidence, such as the systematic review published in the Annals of Internal Medicine 1.

From the Research

Pathophysiology of Steroids for Lower Back Pain

The use of steroids in the treatment of lower back pain is a common practice, but its effectiveness and potential harms are still being researched.

  • Systemic Corticosteroids: Systemic corticosteroids have been used to treat various types of low back pain, including radicular back pain and non-radicular back pain 2. The evidence suggests that systemic corticosteroids may slightly decrease pain and improve function in people with radicular low back pain, but the effects are generally small and not sustained.
  • Epidural Corticosteroid Injections: Epidural corticosteroid injections are also used to treat low back pain, particularly for radiculopathy and spinal stenosis 3. The evidence suggests that these injections may provide immediate reductions in pain and function, but the benefits are generally small and not sustained.
  • Dose and Duration of Corticosteroid Therapy: The optimal dose and duration of corticosteroid therapy for low back pain are still unclear 4. Some studies suggest that lower doses of corticosteroids may be as effective as higher doses, with fewer adverse effects.
  • Oral Corticosteroids: Oral corticosteroids, such as prednisone, are sometimes used to treat low back pain in the emergency department setting 5. However, the evidence suggests that these medications may not provide significant benefits for patients with musculoskeletal low back pain.

Potential Harms of Steroids for Lower Back Pain

While steroids may provide some benefits for low back pain, they can also have potential harms.

  • Adverse Events: Systemic corticosteroids and epidural corticosteroid injections can be associated with adverse events, such as hyperglycemia and serious adverse effects 2, 3.
  • Limited Evidence: The evidence for the effectiveness of steroids for low back pain is generally limited, and more research is needed to fully understand their benefits and harms 6.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.