From the Research
High HDL levels generally don't require treatment as HDL is often considered "good cholesterol" that helps remove other forms of cholesterol from the bloodstream. However, extremely high HDL levels (above 100 mg/dL) might indicate certain genetic conditions or medication effects that warrant attention. If treatment is needed, the approach typically focuses on addressing underlying causes rather than directly lowering HDL. This might include adjusting medications that raise HDL (like estrogen, certain antihypertensives, or statins), managing alcohol consumption (as excessive drinking can elevate HDL), and treating any underlying conditions like thyroid disorders or primary biliary cirrhosis. Unlike with high LDL cholesterol, there are no specific medications designed to lower HDL levels. Lifestyle modifications like maintaining a healthy weight, regular exercise, and a balanced diet are generally recommended for overall cardiovascular health, though these typically raise rather than lower HDL 1. Some studies suggest that increasing HDL-C concentrations has become a potentially attractive therapeutic target for individuals who are at increased risk of CVD, including those with metabolic syndrome 2. It's also worth noting that high-density lipoprotein (HDL) has anti-inflammatory and anti-oxidant activities, which are associated with protection from cardiovascular disease 3. If you have unusually high HDL levels, it's essential to discuss with your healthcare provider to determine if there's an underlying cause that needs addressing or if it represents a genetic variation that doesn't require intervention. Key points to consider include:
- HDL is considered "good cholesterol"
- Extremely high HDL levels may indicate genetic conditions or medication effects
- Treatment focuses on addressing underlying causes, not directly lowering HDL
- Lifestyle modifications are recommended for overall cardiovascular health
- HDL has anti-inflammatory and anti-oxidant activities that protect against cardiovascular disease 3.