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Last updated: June 25, 2025View editorial policy

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Differential Diagnosis for Heel Pain

  • Single most likely diagnosis
    • Plantar fasciitis: This is the most common cause of heel pain, resulting from inflammation of the plantar fascia, a band of tissue that runs along the bottom of the foot. It is often associated with overuse, poor foot mechanics, or inadequate footwear.
  • Other Likely diagnoses
    • Achilles tendinitis: Inflammation of the Achilles tendon, which connects the calf muscles to the heel bone, can cause heel pain, especially in individuals who engage in activities that involve running or jumping.
    • Heel spur: A bony growth on the underside of the heel bone, which can cause pain when walking or standing.
    • Bursitis: Inflammation of the fluid-filled sacs (bursae) that cushion the joints and reduce friction between bone and soft tissue can lead to heel pain.
    • Fat pad atrophy: Thinning of the fat pad under the heel can cause pain, especially in older adults.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Osteomyelitis: A bone infection that can cause heel pain, redness, and swelling. It requires prompt antibiotic treatment to prevent serious complications.
    • Tumor: Although rare, tumors such as osteoid osteoma or Ewing's sarcoma can cause heel pain and should not be missed.
    • Fracture: A stress fracture or other types of fractures in the heel can cause severe pain and require immediate medical attention.
  • Rare diagnoses
    • Rheumatoid arthritis: An autoimmune disorder that can cause heel pain, stiffness, and swelling, especially in the morning.
    • Gout: A form of arthritis characterized by sudden, severe attacks of pain, swelling, and redness, which can occur in the heel.
    • Nerve entrapment: Compression or irritation of the nerves in the foot can cause heel pain, numbness, or tingling.
    • Infection: Cellulitis, abscess, or other infections can cause heel pain, redness, and swelling, and require prompt medical attention.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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