Can exposure to ionizing radiation cause Gastroesophageal Reflux Disease (GERD)?

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Last updated: June 26, 2025View editorial policy

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From the Research

There is no established direct link between exposure to ionizing radiation and the development of Gastroesophageal Reflux Disease (GERD). The most recent and highest quality study on the topic of GERD risk factors is from 2021 1, which focuses on lifestyle and dietary factors, but does not mention ionizing radiation as a risk factor. GERD is primarily caused by dysfunction of the lower esophageal sphincter, which allows stomach acid to flow back into the esophagus. The main risk factors for GERD include:

  • Obesity
  • Pregnancy
  • Smoking
  • Certain medications
  • Hiatal hernia While radiation therapy to the chest or abdomen can cause various gastrointestinal side effects such as esophagitis, nausea, or vomiting, these are typically acute effects rather than chronic GERD. Radiation can cause tissue inflammation and damage, but this doesn't typically manifest as the specific mechanical dysfunction seen in GERD. If you're experiencing GERD symptoms after radiation exposure, it's more likely due to other factors such as stress, dietary changes, or medications associated with your treatment rather than direct radiation effects.

Treatment for GERD typically includes:

  • Lifestyle modifications (avoiding trigger foods, eating smaller meals, not lying down after eating)
  • Over-the-counter medications like antacids, H2 blockers (famotidine, ranitidine), or proton pump inhibitors (omeprazole, esomeprazole)
  • In severe cases, surgical interventions may be considered. Studies on ionizing radiation and its effects on human health, such as those from 2014 2, 2016 3, 4, and 2009 5, do not provide evidence of a direct link between ionizing radiation and GERD. Therefore, the current evidence does not support a causal relationship between exposure to ionizing radiation and the development of GERD.

References

Research

Ionizing radiation injuries and illnesses.

Emergency medicine clinics of North America, 2014

Research

Exposure to low-dose ionizing radiation from medical imaging procedures.

The New England journal of medicine, 2009

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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