Can Seroquel (quetiapine) help with night terrors?

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From the Research

Seroquel (quetiapine) is not the first-line treatment for night terrors, and its use should be carefully considered due to potential side effects. When evaluating the provided evidence, it's clear that none of the studies directly support the use of Seroquel for night terrors. However, the most recent and relevant study regarding the treatment of night terrors is from 2001, which suggests that paroxetine, a selective serotonin re-uptake inhibitor, can be effective in treating severe parasomnias, including night terrors 1. Other studies, such as those from 1994 and 1983, also support the use of medications like paroxetine and benzodiazepines for treating night terrors and somnambulism 2, 3. Additionally, a study from 1983 found midazolam to be effective in eliminating night terrors in children 4. Considering the potential side effects and the lack of direct evidence supporting its use for night terrors, Seroquel should not be the initial choice for treating night terrors. Instead, patients should first try non-medication approaches, and if night terrors persist, other medications like certain antidepressants or benzodiazepines might be considered under careful medical supervision. Key considerations in managing night terrors include:

  • Maintaining regular sleep schedules
  • Reducing stress
  • Avoiding alcohol and caffeine before bed
  • Treating underlying conditions like sleep apnea or PTSD
  • Careful monitoring for side effects if medication is necessary.

References

Research

Successful treatment of severe parasomnias with paroxetine in a 12-year-old boy.

International journal of psychiatry in clinical practice, 2001

Research

Successful treatment of night terrors and somnambulism with paroxetine.

The British journal of psychiatry : the journal of mental science, 1994

Research

Efficacy and safety of midazolam in the treatment of night terrors in children.

British journal of clinical pharmacology, 1983

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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