Fibromyalgia: A condition characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory, and mood issues. It's a common cause of sudden global joint pain, especially in the absence of other systemic symptoms.

Rheumatoid Arthritis (RA): An autoimmune disorder that can cause sudden onset of pain and stiffness in multiple joints, often symmetrically. Morning stiffness lasting more than an hour is a hallmark.
Osteoarthritis (OA): Although OA typically presents with gradual onset, sudden worsening of symptoms can occur, especially after trauma or overuse. It's more common in older adults and affects weight-bearing joints and the hands.
Viral Arthritis: Certain viral infections, like parvovirus B19, can cause sudden onset of global joint pain. This is often accompanied by other systemic symptoms like fever and rash.
Seronegative Spondyloarthropathies: Conditions like ankylosing spondylitis, psoriatic arthritis, and reactive arthritis can present with sudden joint pain, although they typically have other distinguishing features like back pain, psoriasis, or recent infections.

Septic Arthritis: A medical emergency where a joint becomes infected, leading to sudden, severe pain, swelling, and decreased range of motion in one or more joints. Prompt diagnosis and treatment are crucial to prevent joint destruction.
Lyme Disease: Caused by the bacterium Borrelia burgdorferi, transmitted by tick bites. It can cause sudden onset of joint pain, especially in the knees, and is accompanied by other symptoms like fever, headache, and a characteristic rash.
Gout: A form of inflammatory arthritis characterized by sudden, severe attacks of pain, swelling, redness, and tenderness in one or more joints, often occurring at the base of the big toe. It can be triggered by diet, alcohol, or certain medications.
Hemochromatosis: A genetic disorder causing the body to absorb too much iron from food, leading to iron overload. It can cause joint pain similar to OA, among other systemic symptoms.

Relapsing Polychondritis: A rare autoimmune disorder that causes recurring episodes of cartilage inflammation, leading to joint pain, among other symptoms like ear and nose cartilage involvement.
Multicentric Reticulohistiocytosis: A rare condition characterized by the proliferation of histiocytes, leading to skin and joint lesions, and can cause sudden onset of global joint pain.
Sarcoidosis: An inflammatory disease that affects multiple organs in the body, including the joints, causing pain and stiffness. It's rare but can present with sudden global joint pain among other systemic symptoms.