What is the treatment for non-septic bursitis, including the dosage of Keflex (cephalexin)?

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From the FDA Drug Label

Adults The adult dosage ranges from 1 to 4 g daily in divided doses. The usual adult dose is 250 mg every 6 hours For the following infections, a dosage of 500 mg may be administered every 12 hours: streptococcal pharyngitis, skin and skin structure infections, and uncomplicated cystitis in patients over 15 years of age.

The treatment for non-septic bursitis may include antibiotics such as Keflex (cephalexin). The recommended dosage of Keflex for adults is 250 mg every 6 hours or 500 mg every 12 hours for skin and skin structure infections.

  • The dosage range is 1 to 4 g daily in divided doses.
  • For more severe infections, larger doses may be needed. 1

From the Research

The treatment for non-septic bursitis primarily involves rest, ice, compression, and elevation (RICE) of the affected area, along with non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (400-800mg three times daily) or naproxen (500mg twice daily) to reduce pain and inflammation. Keflex (cephalexin) is not typically indicated for non-septic bursitis as antibiotics are unnecessary without infection 2, 3, 4, 5, 6. If the bursitis is severe or persistent, aspiration of fluid from the bursa may be performed, sometimes followed by a corticosteroid injection to reduce inflammation. For recurrent cases, physical therapy focusing on strengthening surrounding muscles and improving flexibility can help prevent future episodes. Patients should avoid activities that put pressure on the affected area and consider protective padding when returning to activities. If symptoms worsen, develop fever, or the area becomes increasingly red, hot, and tender, this may indicate septic bursitis requiring medical evaluation for appropriate antibiotic therapy. Some key points to consider in the management of non-septic bursitis include:

  • Avoiding activities that aggravate the condition
  • Using NSAIDs for pain and inflammation
  • Considering corticosteroid injections for severe or persistent cases
  • Implementing physical therapy to strengthen surrounding muscles and improve flexibility
  • Monitoring for signs of septic bursitis, such as increased redness, heat, or tenderness, which would require prompt medical attention. The most recent and highest quality study 3 supports the use of conservative measures, including rest, NSAIDs, and corticosteroid injections, as the primary treatment for non-septic bursitis.

References

Research

Clinical inquiries. How should you treat trochanteric bursitis?

The Journal of family practice, 2009

Research

Four common types of bursitis: diagnosis and management.

The Journal of the American Academy of Orthopaedic Surgeons, 2011

Research

Septic bursitis.

Seminars in arthritis and rheumatism, 1995

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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