What percentage of gonorrhea and chlamydia is asymptomatic in men?

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Last updated: July 2, 2025View editorial policy

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From the Research

Approximately 40.73% of chlamydia and gonorrhea infections in men are asymptomatic, with a significant portion of these infections being missed if only urethral screening is performed. This is based on the most recent and highest quality study available, which found that among men who have sex with men, the overall prevalence of chlamydia or gonorrhea was 16.05%, with 40.73% of those testing positive being asymptomatic 1. The study also found that anorectal infection was the most common site of infection for chlamydia, followed by urethral and oral infection, while oral infection was the most common site of infection for gonorrhea, followed by anal and urethral infection.

The asymptomatic nature of these infections is particularly concerning because without symptoms, infected individuals may not seek testing or treatment, allowing the infections to persist and potentially cause complications such as epididymitis or urethral stricture, as well as transmission to sexual partners. This is why routine STI screening is recommended for sexually active individuals, especially those with multiple partners, even in the absence of symptoms. Early detection and treatment with appropriate antibiotics can prevent complications and further transmission of these infections.

Some studies have found that the prevalence of asymptomatic infections may be even higher, with one study finding that approximately 85% of rectal infections were asymptomatic 2. However, the study by 1 provides the most recent and highest quality evidence on this topic, and its findings should be given the most weight.

In terms of the specific percentages of asymptomatic infections, the study by 1 found that 40.73% of men who tested positive for chlamydia or gonorrhea were asymptomatic. This is consistent with other studies that have found that a significant portion of chlamydia and gonorrhea infections in men are asymptomatic 3. However, the exact percentage of asymptomatic infections may vary depending on the population being studied and the methods used to detect the infections.

Overall, the evidence suggests that a significant portion of chlamydia and gonorrhea infections in men are asymptomatic, and that routine STI screening is necessary to detect and treat these infections, even in the absence of symptoms.

Key points to consider:

  • The prevalence of asymptomatic chlamydia and gonorrhea infections in men is significant, with approximately 40.73% of infections being asymptomatic 1.
  • Routine STI screening is recommended for sexually active individuals, especially those with multiple partners, even in the absence of symptoms.
  • Early detection and treatment with appropriate antibiotics can prevent complications and further transmission of these infections.
  • The exact percentage of asymptomatic infections may vary depending on the population being studied and the methods used to detect the infections.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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