Does MenaQ7 (Vitamin K2) 180 micrograms (mcg) cause polyuria?

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Last updated: July 5, 2025View editorial policy

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From the Research

There is no established evidence that MenaQ7 (Vitamin K2) at a dose of 180 micrograms causes polyuria (excessive urination). Vitamin K2 supplements, including the MenaQ7 form which is a specific type of menaquinone (MK-7), are generally well-tolerated at this dosage with no documented association with increased urination 1. The common side effects of Vitamin K2 supplements are minimal and typically do not include changes in urinary patterns. Vitamin K2 primarily functions in the body to help with blood clotting and calcium regulation, directing calcium to bones rather than arteries, which is unrelated to kidney function or urine production.

Some studies have investigated the effects of vitamin K on urinary calcium excretion, but these do not provide evidence of an association between vitamin K2 and polyuria 2. If you're experiencing polyuria while taking MenaQ7, it's more likely due to other factors such as increased fluid intake, certain medications, or underlying health conditions like diabetes or kidney issues. Should you notice persistent polyuria while taking this supplement, it would be advisable to consult with a healthcare provider to identify the actual cause rather than assuming it's related to the Vitamin K2 supplement.

Key points to consider:

  • Vitamin K2 is not known to cause polyuria
  • The supplement is generally well-tolerated at a dose of 180 micrograms
  • Other factors are more likely to cause polyuria, such as increased fluid intake or underlying health conditions
  • Consult a healthcare provider if you experience persistent polyuria while taking MenaQ7.

References

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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