What should I do if I experience blurred vision while taking Macrobid (nitrofurantoin)?

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Last updated: July 6, 2025View editorial policy

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From the Guidelines

If you experience blurred vision while taking Macrobid (nitrofurantoin), you should immediately stop taking the medication and contact your healthcare provider as this could be a sign of a serious side effect, such as ethambutol ocular toxicity, which can present with blurred vision, decreased acuity, and impaired color vision, although Macrobid does not contain ethambutol, the concern for vision changes warrants prompt medical attention 1.

Important Considerations

  • Blurred vision is not a commonly reported side effect of Macrobid, but it can indicate potential neurological complications or an allergic reaction.
  • While waiting to speak with your healthcare provider, avoid driving or operating machinery that requires clear vision.
  • Be prepared to tell your doctor when the blurred vision started, if it's constant or intermittent, and any other symptoms you may be experiencing.
  • Your doctor may need to switch you to a different antibiotic to treat your infection, as nitrofurantoin can occasionally affect the optic nerve or cause other neurological effects, particularly in patients with kidney problems or those who have been on the medication for a prolonged period 1.
  • Never stop an antibiotic without medical guidance, but vision changes warrant prompt medical attention.

Key Points to Discuss with Your Healthcare Provider

  • The onset and duration of blurred vision
  • Any other symptoms you are experiencing
  • Your medical history, including any pre-existing kidney problems
  • The potential need to switch to a different antibiotic
  • The importance of regular follow-up to monitor for any further complications or side effects 1

From the FDA Drug Label

Neurologic: ... Benign intracranial hypertension (pseudotumor cerebri), confusion, depression, optic neuritis, and psychotic reactions have been reported rarely.

The FDA drug label mentions that benign intracranial hypertension (pseudotumor cerebri) and optic neuritis have been reported rarely with the use of nitrofurantoin.

  • If you experience blurred vision while taking Macrobid (nitrofurantoin), it is recommended that you contact your healthcare provider immediately.
  • Your healthcare provider may need to discontinue the medication and take appropriate measures to address the issue 2, 2.

From the Research

Macrobid and Blurred Vision

  • Macrobid, also known as nitrofurantoin, is an antibiotic used to treat urinary tract infections.
  • There is no direct evidence in the provided studies that links Macrobid to blurred vision as a side effect 3, 4, 5, 6.
  • However, it is worth noting that the studies provided do not specifically investigate the visual side effects of Macrobid.
  • A study on antiepileptic drugs mentions that non-specific retino- and neurotoxic visual abnormalities, including blurred vision, can occur with certain medications 7.
  • If you are experiencing blurred vision while taking Macrobid, it is recommended to consult your doctor or healthcare provider to determine the cause and appropriate course of action.

Possible Causes of Blurred Vision

  • Blurred vision can be caused by various factors, including medication side effects, eye problems, or other underlying medical conditions.
  • In the context of Macrobid, it is possible that blurred vision could be related to an underlying condition or an interaction with other medications.
  • Further evaluation and consultation with a healthcare professional are necessary to determine the cause of blurred vision and develop an appropriate treatment plan.

Importance of Medical Evaluation

  • If you are experiencing blurred vision or any other unusual symptoms while taking Macrobid, it is essential to seek medical attention.
  • A healthcare professional can evaluate your symptoms, review your medical history, and provide guidance on the best course of action 3, 4, 5, 6.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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